Leucopelargonidin
Encyclopedia
Leucopelargonidin is a colorless chemical compound related to leucoanthocyanins. It can be found in Albizia lebbeck
(East Indian walnut), in the fruit of Anacardium occidentale (Cashew), in the fruit of Areca catechu
(Areca nut), in the fruit of Hydnocarpus wightiana
(Hindi Chaulmoogra), in the rhizome of Rumex hymenosepalus
(Arizona dock), in Zea Mays (Corn) and in Ziziphus jujuba (Chinese date).
(+)-Leucopelargonidin can be synthesized from (+)-dihydrokaempferol by sodium borohydride
reduction.
uses cis-3,4-leucopelargonidin and NADP+
to produce (+)-dihydrokaempferol (aromadedrin), NADPH, and H+.
(2R,3S)-catechin:NADP+ 4-oxidoreductase transforms cis-3,4-leucopelargonidin into afzelechin
.
Albizia lebbeck
Albizia lebbeck is a species of Albizia, native to tropical southern Asia, and widely cultivated and naturalised in other tropical and subtropical regions. English names for it include Lebbeck, Lebbek Tree, Flea Tree, Frywood, Koko and Woman's tongues Tree...
(East Indian walnut), in the fruit of Anacardium occidentale (Cashew), in the fruit of Areca catechu
Areca catechu
Areca catechu is the areca palm or areca nut palm, , a species of palm which grows in much of the tropical Pacific, Asia, and parts of east Africa. The palm is believed to have originated in either Malaysia or the Philippines...
(Areca nut), in the fruit of Hydnocarpus wightiana
Hydnocarpus wightiana
Hydnocarpus wightiana or Chaulmoogra is a tree in the Achariaceae family. The oil from its seeds has been widely used in Indian medicine and Chinese traditional medicine for the treatment of leprosy. It entered early Western medicine in the ninteenth century before the era of sulfones and...
(Hindi Chaulmoogra), in the rhizome of Rumex hymenosepalus
Rumex hymenosepalus
Rumex hymenosepalus, commonly known as canaigre, ganagra, wild rhubarb, Arizona dock, or tanner's dock, is a perennial flowering plant which is native to the United States and Mexico. It has been cultivated in the southwestern United States as the roots are a good source of tannin, for use in...
(Arizona dock), in Zea Mays (Corn) and in Ziziphus jujuba (Chinese date).
(+)-Leucopelargonidin can be synthesized from (+)-dihydrokaempferol by sodium borohydride
Sodium borohydride
Sodium borohydride, also known as sodium tetrahydridoborate, is an inorganic compound with the formula NaBH4. This white solid, usually encountered as a powder, is a versatile reducing agent that finds wide application in chemistry, both in the laboratory and on a technical scale. Large amounts are...
reduction.
Metabolism
Dihydrokaempferol 4-reductaseDihydrokaempferol 4-reductase
In enzymology, a dihydrokaempferol 4-reductase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cis-3,4-leucopelargonidin and NADP+, whereas its 3 products are -dihydrokaempferol, NADPH, and H+....
uses cis-3,4-leucopelargonidin and NADP+
Nicotinamide adenine dinucleotide phosphate
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or TPN in older notation , is a coenzyme used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent....
to produce (+)-dihydrokaempferol (aromadedrin), NADPH, and H+.
(2R,3S)-catechin:NADP+ 4-oxidoreductase transforms cis-3,4-leucopelargonidin into afzelechin
Afzelechin
Afzelechin is a flavan-3ol, a type of flavonoids. It can be found in Bergenia ligulata ....
.