LIMK1
Encyclopedia
LIM domain kinase 1 is an enzyme
that in humans is encoded by the LIMK1 gene
.
with PAK1
, YWHAZ
, PAK4
, Cofilin 1
, Neuregulin 1
and Cyclin-dependent kinase inhibitor 1C
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the LIMK1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
LIMK1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with PAK1
PAK1
Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene.-Interactions:PAK1 has been shown to interact with C-Raf, NCK1, LIMK1, RAC1, ARHGEF2, BMX, ARPC1B, DYNLL1, Cyclin-dependent kinase 5, PAK1IP1 and CDC42....
, YWHAZ
YWHAZ
14-3-3 protein zeta/delta is a protein that in humans is encoded by the YWHAZ gene.-Interactions:YWHAZ has been shown to interact with TSC2, LIMK1, CDC25B, AKT1, BCAR1, Interleukin-9 receptor, C-Raf, HMGN1, Vimentin, Tau protein, Protein kinase Mζ, GP1BB, GP1BA, TNFAIP3, Bcl-2-associated death...
, PAK4
PAK4
Serine/threonine-protein kinase PAK 4 is an enzyme that in humans is encoded by the PAK4 gene.-Interactions:PAK4 has been shown to interact with CDC42, Integrin, beta 5 and LIMK1.-External links:* Info with links in the...
, Cofilin 1
Cofilin 1
Cofilin 1 , also known as CFL1, is a human gene, part of the ADF/cofilin family.Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner...
, Neuregulin 1
Neuregulin 1
Neuregulin 1 or NRG1 is a protein which in humans is encoded by the NRG1 gene. NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. Neuregulin 1 is produced in numerous isoforms by alternative splicing, which allows it to perform a wide variety of functions...
and Cyclin-dependent kinase inhibitor 1C
Cyclin-dependent kinase inhibitor 1C
Cyclin-dependent kinase inhibitor 1C , also known as CDKN1C, is protein which in humans is encoded by the CDKN1C imprinted gene.- Function :...
.
External links
- LIMK1 Info with links in the Cell Migration Gateway