KC6
Encyclopedia
KC6 is a novel gene located on chromosome 18
at p12.3. It was discovered by Rabinowitz et al. (2005) in a study whose aims were finding genes expressed in human cornea
and increasing the knowledge of molecular changes in keratoconus
. It lies adjacent to the PIK3C3
gene. Its function is unknown so far and the only study available is that of its discovery. Authors suggest that the gene may be cornea-specific in its expression.
Chromosome 18 (human)
125px|rightChromosome 18 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 18 spans about 85 million base pairs and represents about 2.5 percent of the total DNA in cells.Identifying genes on each chromosome is an active area of genetic...
at p12.3. It was discovered by Rabinowitz et al. (2005) in a study whose aims were finding genes expressed in human cornea
Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, with the cornea accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is...
and increasing the knowledge of molecular changes in keratoconus
Keratoconus
Keratoconus , is a degenerative disorder of the eye in which structural changes within the cornea cause it to thin and change to a more conical shape than its normal gradual curve....
. It lies adjacent to the PIK3C3
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme that in humans is encoded by the PIK3C3 gene.-Further reading:...
gene. Its function is unknown so far and the only study available is that of its discovery. Authors suggest that the gene may be cornea-specific in its expression.