Josef Jadassohn
Encyclopedia
Joseph Jadassohn (September 10, 1863, Liegnitz - March 24, 1936, Zurich
Zürich
Zurich is the largest city in Switzerland and the capital of the canton of Zurich. It is located in central Switzerland at the northwestern tip of Lake Zurich...

) was a German
Germans
The Germans are a Germanic ethnic group native to Central Europe. The English term Germans has referred to the German-speaking population of the Holy Roman Empire since the Late Middle Ages....

 dermatologist.

He was an assistant to Albert Neisser at the Allerheiligen-Hospital in Breslau until 1892, the director of the university skin clinic in Bern (1896-1917), and later a professor of dermatology at Breslau University (1917-1932).

Jadassohn was among the first to take an immunological
Immunology
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders ; the...

 approach in research of dermatological disorders, and contributed to the understanding of the immunopathology
Immunopathology
Immunopathology is a branch of medicine that deals with immune responses associated with disease. It includes the study of the pathology of an organism, organ system, or disease with respect to the immune system, immunity, and immune responses....

 of tuberculosis
Tuberculosis
Tuberculosis, MTB, or TB is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body...

 and trichophytosis
Favus
Favus is a disease usually affecting the scalp, but occurring occasionally on any part of the skin, and even at times on mucous membranes.-Presentation:...

. He was a pioneer in the field of allergology, and is credited for introducing patch test
Patch test
Patch test may refer to*Patch test *Patch test...

ing for diagnosis of contact dermatitis
Contact dermatitis
Contact dermatitis is a term for a skin reaction resulting from exposure to allergens or irritants . Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight....

, In 1901 he described a rare childhood dermatological disorder known as granulosis rubra nasi
Granulosis rubra nasi
Granulosis rubra nasi is a rare familial disease of children, occurring on the nose, cheeks, and chin, characterized by diffuse redness, persistent hyperhidrosis, and small dark red papules that disappear on diascopic pressure....

.

Conditions

Two of the dermatological disorders named after him are: "Jadassohn's disease I" (a skin disorder originating at the elbow
Elbow
The human elbow is the region surrounding the elbow-joint—the ginglymus or hinge joint in the middle of the arm. Three bones form the elbow joint: the humerus of the upper arm, and the paired radius and ulna of the forearm....

} and "Jadassohn's disease II" (a natal skin disorder affecting the face and scalp). Together with his assistants Walter Dössekker (1868-1962), Max Tièche (1878-1938) and Felix Lewandowsky
Felix Lewandowsky
Felix Lewandowsky was a German dermatologist who was a native of Hamburg.-Biography:He was born on October 1, 1879 and in 1902 he earned his doctorate at Strassburg. From 1903 until 1907 he worked at the dermatological clinic in Bern where he was an assistant to Josef Jadassohn...

 (1879-1921), he shares a handful of eponymous medical conditions, including:
  • Jadassohn-Dössekker disease: Also known as atypical tuberous myxedema
    Myxedema
    Myxedema describes a specific form of cutaneous and dermal edema secondary to increased deposition of connective tissue components in subcutaneous tissue as seen in various forms of hypothyroidism and Graves' disease. It is more common in women than in men...

    .
  • Tièche-Jadassohn naevus: A hard, dark blue, benign melanocytic
    Melanocyte
    -External links: - "Eye: fovea, RPE" - "Integument: pigmented skin"...

     tumor.
  • Jadassohn-Lewandowsky syndrome: An ectodermal dysplasia
    Dysplasia
    Dysplasia , is a term used in pathology to refer to an abnormality of development. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells. Dysplasia is often indicative of an early neoplastic process...

     characterized by onychogryposis, hyperkeratosis
    Hyperkeratosis
    Hyperkeratosis is thickening of the stratum corneum, often associated with a qualitative abnormality of the keratin, and also usually accompanied by an increase also in the granular layer...

    , leukoplakia
    Leukoplakia
    Leukoplakia is a clinical term used to describe patches of keratosis. It is visible as adherent white patches on the mucous membranes of the oral cavity, including the tongue, but also other areas of the gastro-intestinal tract, urinary tract and the genitals. The clinical appearance is highly...

    , hyperhidrosis
    Hyperhidrosis
    Hyperhidrosis is the condition characterized by abnormally increased perspiration, in excess of that required for regulation of body temperature.-Classification:Hyperhidrosis can either be generalized or localized to specific parts of the body...

     and pachyonychia congenita
    Pachyonychia congenita
    Pachyonychia congenita, also called Jadassohn-Lewandowski Syndrome or simply pachyonychia, is an autosomal dominant skin disorder.-Symptoms:Common symptoms include:*Excess keratin in nail beds and thickening of the nails...

    .

Literary works

Jadassohn published a revision of Edmund Lesser
Edmund Lesser
Edmund Lesser was a German dermatologist who was a native of Neisse.He studied medicine at the Universities of Berlin, Bonn and Strasbourg, and in 1876 earned his medical doctorate. Later he became an assistant to Oskar Simon at the dermatological clinic in Breslau, and in 1882 received his...

’s Lehrbuch der Haut- und Geschlechtskrankheiten (14th edition, 1927-30), and from 1927 published the multi-volume Handbuch für Haut- und Geschlechtskrankheiten. Other noted written works of his include:
  • Die venerischen Krankheiten, (1901)
  • Ueber eine eigenartige Erkrankung der Nasenhaut bei Kindern (Granulosis rubra nasi). Archiv für Dermatologie und Syphilis, Wien, 1901, 58: 145-158
  • Die Tuberkulose der Haut. In: Franz Mracek's Handbuch der Hautkrankheiten (1904)
  • Allgemeine Ätiologie, Pathologie, Diagnose und Therapie der Gonorrhoe, (1910)
  • Dermatologie, (1938)

External links

  • Josef Jadassohn @ Who Named It
    Who Named It
    Who Named It? is an English-language dictionary of medical eponyms and the people associated with their identification. Though this is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliographies. It is hosted in Norway and maintained by medical...

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