Jones' stain, also Jones stain, is a methenamine silver-Periodic acid

Periodic acid

Periodic acid, or iodic acid is an oxoacid of iodine having chemical formula HIO4 or H5IO6.In dilute aqueous solution, periodic acid exists as discrete hydronium and metaperiodate ions. When more concentrated, orthoperiodic acid, H5IO6, is formed; this dissociates into hydronium and...

-Schiff stain used in pathology

Pathology

Pathology is the precise study and diagnosis of disease. The word pathology is from Ancient Greek , pathos, "feeling, suffering"; and , -logia, "the study of". Pathologization, to pathologize, refers to the process of defining a condition or behavior as pathological, e.g. pathological gambling....

. It is also referred to as methenamine PAS which is commonly abbreviated MPAS.

It stains for basement membrane

Basement membrane

The basement membrane is a thin sheet of fibers that underlies the epithelium, which lines the cavities and surfaces of organs including skin, or the endothelium, which lines the interior surface of blood vessels.- Composition :...

 and is widely used in the investigation of medical kidney diseases.

The Jones stain demonstrates the spiked GBM

GBM

-Medicine:* Glioblastoma multiforme, a type of brain tumor* Glomerular basement membrane, a part of the glomerulus which helps separate urine from blood-Other:* Game Boy Micro, a portable video game system from Nintendo...

, caused by subepithelial deposits, seen in membranous nephropathy.