John Gofman
Encyclopedia
John William Gofman was an American scientist and advocate. He was Professor Emeritus of Molecular and Cell Biology at University of California at Berkeley. Some of his early work was on the Manhattan Project
Manhattan Project
The Manhattan Project was a research and development program, led by the United States with participation from the United Kingdom and Canada, that produced the first atomic bomb during World War II. From 1942 to 1946, the project was under the direction of Major General Leslie Groves of the US Army...

, and he shares patents on the fissionability of uranium-233
Uranium-233
Uranium-233 is a fissile isotope of uranium, bred from Thorium as part of the thorium fuel cycle. It has been used in a few nuclear reactors and has been proposed for much wider use as a nuclear fuel. It has a half-life of 160,000 years....

 as well as on early processes for separating plutonium
Plutonium
Plutonium is a transuranic radioactive chemical element with the chemical symbol Pu and atomic number 94. It is an actinide metal of silvery-gray appearance that tarnishes when exposed to air, forming a dull coating when oxidized. The element normally exhibits six allotropes and four oxidation...

 from fission products. Dr. Gofman later worked in medicine and led the team that discovered and characterized lipoprotein
Lipoprotein
A lipoprotein is a biochemical assembly that contains both proteins and lipids water-bound to the proteins. Many enzymes, transporters, structural proteins, antigens, adhesins, and toxins are lipoproteins...

s in the causation of heart disease
Heart disease
Heart disease, cardiac disease or cardiopathy is an umbrella term for a variety of diseases affecting the heart. , it is the leading cause of death in the United States, England, Canada and Wales, accounting for 25.4% of the total deaths in the United States.-Types:-Coronary heart disease:Coronary...

. In 1963, he established the Biomedical Research Division for the Livermore National Laboratory, where he was on the cutting edge of research into the connection between chromosomal abnormalities and cancer.

Later in life, he took on a role as an advocate warning of dangers involved with nuclear power (see Nuclear power debate
Nuclear power debate
The nuclear power debate is about the controversy which has surrounded the deployment and use of nuclear fission reactors to generate electricity from nuclear fuel for civilian purposes...

). From 1971 onward, he was the Chairman of the Committee for Nuclear Responsibility
Committee for Nuclear Responsibility
The Committee for Nuclear Responsibility was formed as a "political and educational organization to disseminate anti-nuclear views and information to the public"...

. He also described himself a libertarian and spoke at several events sponsored by the Students for a Libertarian Society
Students for a Libertarian Society
Students for a Libertarian Society is an activist organization for students in the United States who want to promote libertarian ideals on college campuses.- Origins :...

 in 1979 and 1980. He was awarded the Right Livelihood Award
Right Livelihood Award
The Right Livelihood Award, also referred to as the "Alternative Nobel Prize", is a prestigious international award to honour those "working on practical and exemplary solutions to the most urgent challenges facing the world today". The prize was established in 1980 by Jakob von Uexkull, and is...

 for his work on the effects of the Chernobyl disaster
Chernobyl disaster
The Chernobyl disaster was a nuclear accident that occurred on 26 April 1986 at the Chernobyl Nuclear Power Plant in Ukraine , which was under the direct jurisdiction of the central authorities in Moscow...

's low-level radiation exposure on the population. John Gofman died of heart failure on August 15, 2007 in his home in San Francisco.

Early work

John Gofman was born in Cleveland, Ohio
Cleveland, Ohio
Cleveland is a city in the U.S. state of Ohio and is the county seat of Cuyahoga County, the most populous county in the state. The city is located in northeastern Ohio on the southern shore of Lake Erie, approximately west of the Pennsylvania border...

. He graduated from Oberlin College
Oberlin College
Oberlin College is a private liberal arts college in Oberlin, Ohio, noteworthy for having been the first American institution of higher learning to regularly admit female and black students. Connected to the college is the Oberlin Conservatory of Music, the oldest continuously operating...

 with a bachelor's in 1939, and received a doctorate in nuclear and physical chemistry from Berkeley in 1943. In his work as a graduate student, he studied nuclear isotopes and helped to describe several discoveries, including protactinium
Protactinium
Protactinium is a chemical element with the symbol Pa and atomic number 91. It is a dense, silvery-gray metal which readily reacts with oxygen, water vapor and inorganic acids. It forms various chemical compounds where protactinium is usually present in the oxidation state +5, but can also assume...

-232, uranium-232, protactinium-233, and uranium-233
Uranium-233
Uranium-233 is a fissile isotope of uranium, bred from Thorium as part of the thorium fuel cycle. It has been used in a few nuclear reactors and has been proposed for much wider use as a nuclear fuel. It has a half-life of 160,000 years....

. He also helped to work out the fissionability of uranium-233. He later became the group co-leader of the Plutonium Project, an offshoot of the Manhattan Project
Manhattan Project
The Manhattan Project was a research and development program, led by the United States with participation from the United Kingdom and Canada, that produced the first atomic bomb during World War II. From 1942 to 1946, the project was under the direction of Major General Leslie Groves of the US Army...

.

Dr. Gofman earned his medical degree from the University of California, San Francisco
University of California, San Francisco
The University of California, San Francisco is one of the world's leading centers of health sciences research, patient care, and education. UCSF's medical, pharmacy, dentistry, nursing, and graduate schools are among the top health science professional schools in the world...

, in 1946. After that, he and his collaborators investigated the body’s lipoprotein
Lipoprotein
A lipoprotein is a biochemical assembly that contains both proteins and lipids water-bound to the proteins. Many enzymes, transporters, structural proteins, antigens, adhesins, and toxins are lipoproteins...

s, which contain both protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

s and fat
Fat
Fats consist of a wide group of compounds that are generally soluble in organic solvents and generally insoluble in water. Chemically, fats are triglycerides, triesters of glycerol and any of several fatty acids. Fats may be either solid or liquid at room temperature, depending on their structure...

s, and their circulation within the bloodstream. The researchers described low-density and high-density lipoproteins and their roles in metabolic disorders and coronary disease. This work continued throughout the late 1940s and early 1950s.

At Livermore

Dr. Gofman established the Biomedical Research Division for the Lawrence Livermore National Laboratory
Lawrence Livermore National Laboratory
The Lawrence Livermore National Laboratory , just outside Livermore, California, is a Federally Funded Research and Development Center founded by the University of California in 1952...

 in 1963. In 1964, he raised questions about a lack of data on low-level radiation and also proposed a wide-ranging study of exposure in medicine and the workplace at a symposium for nuclear scientists and engineers. This helped start a national inquiry into the safety of atomic power. With his colleague Dr. Arthur R. Tamplin, Dr. Gofman then looked at health studies of the survivors of Hiroshima and Nagasaki, as well as other epidemiological studies, and conducted research on radiation’s influences on human chromosomes. The two scientists suggested that federal safety guidelines for low-level exposures be reduced by 90 percent in 1969. The Atomic Energy Commission
United States Atomic Energy Commission
The United States Atomic Energy Commission was an agency of the United States government established after World War II by Congress to foster and control the peace time development of atomic science and technology. President Harry S...

 contested the findings, and "the furor made Dr. Gofman a reluctant figurehead of the anti-nuclear movement
Anti-nuclear movement in the United States
The anti-nuclear movement in the United States consists of more than 80 anti-nuclear groups which have acted to oppose nuclear power or nuclear weapons, or both, in the United States. These groups include the Abalone Alliance, Clamshell Alliance, Institute for Energy and Environmental Research,...

" according to The New York Times. In 1970, he testified in favor of a bill to ban commercial nuclear reactors in New York City and told the City Council that a reactor in an urban environment would be "equal in the opposite direction to all the medical advances put together in the last 25 years."

Opposition to nuclear power

Gofman retired as a teaching professor in 1973 and became a professor emeritus of molecular and cell biology.

Gofman testified on the behalf of Samuel Lovejoy
Montague Nuclear Power Plant
The Montague Nuclear Power Plant was to consist of two 1,150-megawatt nuclear reactors to be located in Montague, Massachusetts. The project was proposed in 1973 and canceled in 1980, after $29 million was spent on the project....

 at Lovejoy's 1974 trial. Lovejoy was charged with malicious destruction of property for toppling a weather tower in Montague, Massachusetts
Montague, Massachusetts
Montague is a town in Franklin County, Massachusetts, United States. The population was 8,489 at the 2000 census. It is part of the Springfield, Massachusetts metropolitan statistical area....

, owned by Northeast Utilities
Northeast Utilities
Northeast Utilities is a publicly-traded, Fortune 500 energy company headquartered in Berlin, Connecticut, with several regulated subsidiaries offering retail electricity and natural gas service to more than 2.1 million customers in New England....

. Lovejoy's actions were an act of protest against a proposed nuclear power plant
Nuclear power plant
A nuclear power plant is a thermal power station in which the heat source is one or more nuclear reactors. As in a conventional thermal power station the heat is used to generate steam which drives a steam turbine connected to a generator which produces electricity.Nuclear power plants are usually...

 to be built on Montague Plains. Lovejoy was inspired by Gofman's book, Poisoned Power.

After the 1979 Three Mile Island accident
Three Mile Island accident
The Three Mile Island accident was a core meltdown in Unit 2 of the Three Mile Island Nuclear Generating Station in Dauphin County, Pennsylvania near Harrisburg, United States in 1979....

, Gofman used his model of the effects of low-level radiation to predict 333 deaths from the accident; to date no deaths have been officially attributed to the accident. After the April 26, 1986 Chernobyl disaster
Chernobyl disaster
The Chernobyl disaster was a nuclear accident that occurred on 26 April 1986 at the Chernobyl Nuclear Power Plant in Ukraine , which was under the direct jurisdiction of the central authorities in Moscow...

, he predicted one million malignancies from the fallout, half of which would be fatal. According to the United Nations, the official death toll to date is 56, of which nine were children who died of thyroid cancer
Thyroid cancer
Thyroid neoplasm is a neoplasm or tumor of the thyroid. It can be a benign tumor such as thyroid adenoma, or it can be a malignant neoplasm , such as papillary, follicular, medullary or anaplastic thyroid cancer. Most patients are 25 to 65 years of age when first diagnosed; women are more affected...

 (although many animals died from that cause), as well as 4,000 eventual extra cancer deaths. Greenpeace
Greenpeace
Greenpeace is a non-governmental environmental organization with offices in over forty countries and with an international coordinating body in Amsterdam, The Netherlands...

 and others disputes the U.N. fatality number. Amory Lovins, in a Huffington Post op-ed
Op-ed
An op-ed, abbreviated from opposite the editorial page , is a newspaper article that expresses the opinions of a named writer who is usually unaffiliated with the newspaper's editorial board...

, claims support for his skeptical views on such estimates from a book translated from Russian and reprinted by the New York Academy of Sciences, which he says cited
5,000 mainly Slavic-language scientific papers the IAEA overlooked. It found deaths approaching a million through 2004, nearly 170,000 of them in North America. The total toll now exceeds a million, plus a half-trillion dollars' economic damage.


After a speech Gofman gave on nuclear waste at a national conference of activists in the summer of 1990, Charles Butler approached him for help. Butler was a retired physicist living in the Mojave Desert
Mojave Desert
The Mojave Desert occupies a significant portion of southeastern California and smaller parts of central California, southern Nevada, southwestern Utah and northwestern Arizona, in the United States...

 town of Needles, California
Needles, California
Needles is a city located in the Mojave Desert on the western banks of the Colorado River in San Bernardino County, California. It is located in the Mohave Valley, which straddles the California–Arizona border. The city is accessible via Interstate 40 and U.S. Route 95...

, and was looking for help to stop the proposed low-level nuclear waste facility at Ward Valley, California. Gofman referred him to the Abalone Alliance
Abalone alliance
The Abalone Alliance was a nonviolent civil disobedience group formed to shut down the Pacific Gas and Electric Company's Diablo Canyon Power Plant near San Luis Obispo on the central California coast in the United States...

 Clearinghouse in San Francisco. With less than two weeks before the closure of the Environmental Impact Statement
Environmental impact statement
An environmental impact statement , under United States environmental law, is a document required by the National Environmental Policy Act for certain actions "significantly affecting the quality of the human environment". An EIS is a tool for decision making...

, the Alliance was able to mount a letter writing campaign that helped delay the EIS for an additional 90 days. This initial delay gave activists the time to form Don't Waste California and build a grassroots campaign that eventually stopped Ward Valley from opening.

Gofman also did work on the Diablo Canyon Power Plant
Diablo Canyon Power Plant
Diablo Canyon Power Plant is an electricity-generating nuclear power plant at Avila Beach in San Luis Obispo County, California. The plant has two Westinghouse-designed 4-loop pressurized-water nuclear reactors operated by Pacific Gas & Electric. The facility is located on about in Avila Beach,...

.

Legacy

Gofman promoted a linear no-threshold model
Linear no-threshold model
The linear no-threshold model is a method for predicting the long term, biological damage caused by ionizing radiation and is based on the assumption that the risk is directly proportional to the dose at all dose levels....

 for the dangers of radiation, suggesting that even small doses over time could prove harmful. His 1981 book Radiation and Human Health expounded on this and gave prediction tables for how much average life expectancy might be affected by radiation.

Awards

  • Gold-Headed Cane Award, University of California Medical School, 1946, presented to the graduating senior who most fully personifies the qualities of a "true physician."
  • Modern Medicine Award, 1954, for outstanding contributions to heart disease research.
  • The Lyman Duff Lectureship Award of the American Heart Association in 1965, for research in atherosclerosis and coronary heart disease; lecture published in 1966 as "Ischemic Heart Disease, Atherosclerosis, and Longevity," in Circulation 34: 679-697.
  • The Stouffer Prize (shared) 1972, for outstanding contributions to research in arterioslerosis.
  • American College of Cardiology, 1974; selection as one of twenty-five leading researchers in cardiology of the past quarter-century.
  • University of California, Berkeley, Bancroft Library, 1988; announcement of the "Gofman Papers" established in the History of Science and Technology Special Collection (October 1988, Bancroftiana, No. 97: 10-11).
  • Right livelihood Award, 1992
  • Honored Speaker for the Meeting of the Arteriosclerosis Section of the American Heart Association, 1993

See also

  • Alice Stewart
    Alice Stewart
    Dr Alice Mary Stewart was a physician and epidemiologist specialising in social medicine and the effects of radiation on health...

  • Ernest Sternglass
  • Linear no-threshold model
    Linear no-threshold model
    The linear no-threshold model is a method for predicting the long term, biological damage caused by ionizing radiation and is based on the assumption that the risk is directly proportional to the dose at all dose levels....

  • Edward B. Lewis
    Edward B. Lewis
    - External links :* *...


External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
x
OK