Jean Lobstein
Encyclopedia
Jean Georges Chrétien Frédéric Martin Lobstein (German spelling: Johann Friedrich Georg Christian Martin Lobstein) (May 8, 1777 - March 7, 1835) was a German-born, French pathologist and surgeon
Surgeon
In medicine, a surgeon is a specialist in surgery. Surgery is a broad category of invasive medical treatment that involves the cutting of a body, whether human or animal, for a specific reason such as the removal of diseased tissue or to repair a tear or breakage...

 who was a native of Giessen.

In 1803 he earned his doctorate at the University of Strasbourg
University of Strasbourg
The University of Strasbourg in Strasbourg, Alsace, France, is the largest university in France, with about 43,000 students and over 4,000 researchers....

, and subsequently was an anatomical
Anatomy
Anatomy is a branch of biology and medicine that is the consideration of the structure of living things. It is a general term that includes human anatomy, animal anatomy , and plant anatomy...

 prosector
Prosector
A prosector is a person with the special task of preparing a dissection for demonstration, usually in medical schools or hospitals. Many important anatomists began their careers as prosectors working for lecturers and demonstrators in anatomy and pathology....

 at Strasbourg. In 1805 he became a professor at école d'obstétrique du Rhin inférieur (School of Obstetrics
Obstetrics
Obstetrics is the medical specialty dealing with the care of all women's reproductive tracts and their children during pregnancy , childbirth and the postnatal period...

 of the Lower Rhine), where he practiced medicine for thirty years. In 1819 he attained the professorship of pathological anatomy. He was a nephew of noted surgeon Johann Friedrich Lobstein (1736-1784).

Jean Lobstein is remembered for several contributions made in the field of pathological anatomy. He described a disorder known today as osteogenesis imperfecta type I
Osteogenesis imperfecta
Osteogenesis imperfecta is a genetic bone disorder. People with OI are born with defective connective tissue, or without the ability to make it, usually because of a deficiency of Type-I collagen...

, which is sometimes called Lobstein's disease. This disease is an hereditary, generalized connective tissue
Connective tissue
"Connective tissue" is a fibrous tissue. It is one of the four traditional classes of tissues . Connective Tissue is found throughout the body.In fact the whole framework of the skeleton and the different specialized connective tissues from the crown of the head to the toes determine the form of...

 disorder characterized by bone fragility and a blue-gray sclera
Sclera
The sclera , also known as the white or white of the eye, is the opaque , fibrous, protective, outer layer of the eye containing collagen and elastic fiber. In the development of the embryo, the sclera is derived from the neural crest...

e of the eyes. In 1813 he founded an impressive pathological museum in Strasbourg
Strasbourg
Strasbourg is the capital and principal city of the Alsace region in eastern France and is the official seat of the European Parliament. Located close to the border with Germany, it is the capital of the Bas-Rhin département. The city and the region of Alsace are historically German-speaking,...

, which remained intact until the years following the Franco-Prussian War
Franco-Prussian War
The Franco-Prussian War or Franco-German War, often referred to in France as the 1870 War was a conflict between the Second French Empire and the Kingdom of Prussia. Prussia was aided by the North German Confederation, of which it was a member, and the South German states of Baden, Württemberg and...

, when its artifacts were either dispersed or lost.

Lobstein's best known publication was an unfinished four-volume work titled Traité d’anatomie pathologique, which was based on his personal experiences as a pathologist. He was an avid archaeologist, historian
Historian
A historian is a person who studies and writes about the past and is regarded as an authority on it. Historians are concerned with the continuous, methodical narrative and research of past events as relating to the human race; as well as the study of all history in time. If the individual is...

 and numismatist, and is credited for coining the term "arteriosclerosis
Arteriosclerosis
Arteriosclerosis refers to a stiffening of arteries.Arteriosclerosis is a general term describing any hardening of medium or large arteries It should not be confused with "arteriolosclerosis" or "atherosclerosis".Also known by the name "myoconditis" which is...

".,

Associated eponym

  • Lobstein's ganglion: Also known as the thoracic splanchnic ganglion, which is a small collection of nerve bodies on the greater thoracic splanchnic nerve
    Thoracic splanchnic nerves
    Thoracic splanchnic nerves are splanchnic nerves that arise from the sympathetic trunk in the thorax and travel inferiorly to provide sympathetic innervation to the abdomen...

    .
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