James Papez
Encyclopedia
James Papez was an American
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 neuroanatomist. Papez received his MD
Doctor of Medicine
Doctor of Medicine is a doctoral degree for physicians. The degree is granted by medical schools...

 from the University of Minnesota
University of Minnesota Medical School
The University of Minnesota Medical School is the medical school of the University of Minnesota. It is a combination of two campuses situated in Minneapolis and Duluth, Minnesota....

 College of Medicine
Medicine
Medicine is the science and art of healing. It encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness....

 and Surgery
Surgery
Surgery is an ancient medical specialty that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, or to help improve bodily function or appearance.An act of performing surgery may be called a surgical...

. He is most famous for his 1937 description of the Papez circuit
Papez circuit
Described by James Papez in 1937, the Papez circuit of the brain is one of the major pathways of the limbic system and is chiefly involved in the cortical control of emotion. The Papez circuit plays a role in storing memory....

 which is a neural
Neuron
A neuron is an electrically excitable cell that processes and transmits information by electrical and chemical signaling. Chemical signaling occurs via synapses, specialized connections with other cells. Neurons connect to each other to form networks. Neurons are the core components of the nervous...

 pathway in the brain
Brain
The brain is the center of the nervous system in all vertebrate and most invertebrate animals—only a few primitive invertebrates such as sponges, jellyfish, sea squirts and starfishes do not have one. It is located in the head, usually close to primary sensory apparatus such as vision, hearing,...

 thought to be involved in the cortical
Cerebral cortex
The cerebral cortex is a sheet of neural tissue that is outermost to the cerebrum of the mammalian brain. It plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It is constituted of up to six horizontal layers, each of which has a different...

 control of emotion
Emotion
Emotion is a complex psychophysiological experience of an individual's state of mind as interacting with biochemical and environmental influences. In humans, emotion fundamentally involves "physiological arousal, expressive behaviors, and conscious experience." Emotion is associated with mood,...

. He was a neurologist at Cornell University when he published a journal article in which he outlined a "new" circuit to account for emotion. He hypothesized that the hippocampus, the cingulate gyrus (Broca's callosal lobe), the hypothalamus, the anterior thalamic nuclei, and the interconnections among these structures constituted a harmonious mechanism which elaborate the functions of emotions. Papez never mentioned Broca's limbic lobe
Limbic lobe
The limbic lobe is an arc-shaped region of cortex on the medial surface of each cerebral hemisphere of the mammalian brain, consisting of parts of the frontal, parietal and temporal lobes...

 but others noted that his circuit was very similar to Broca's great limbic lobe.

See also

  • Papez circuit
    Papez circuit
    Described by James Papez in 1937, the Papez circuit of the brain is one of the major pathways of the limbic system and is chiefly involved in the cortical control of emotion. The Papez circuit plays a role in storing memory....

  • Paul Broca
    Paul Broca
    Pierre Paul Broca was a French physician, surgeon, anatomist, and anthropologist. He was born in Sainte-Foy-la-Grande, Gironde. He is best known for his research on Broca's area, a region of the frontal lobe that has been named after him. Broca’s Area is responsible for articulated language...

  • Paul D. MacLean
  • Limbic system
    Limbic system
    The limbic system is a set of brain structures including the hippocampus, amygdala, anterior thalamic nuclei, septum, limbic cortex and fornix, which seemingly support a variety of functions including emotion, behavior, long term memory, and olfaction. The term "limbic" comes from the Latin...

  • Affective neuroscience
    Affective neuroscience
    Affective neuroscience is the study of the neural mechanisms of emotion. This interdisciplinary field combines neuroscience with the psychological study of personality, emotion, and mood.-Brain areas related to emotion:...

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