Jacqueline Crawley
Encyclopedia
Jacqueline N. Crawley is an American behavioral neuroscientist
and an expert on rodent behavioral analysis. She currently is chief of the Laboratory of Behavioral Neuroscience in the intramural program of the National Institute of Mental Health
. Her translational research
program focuses on testing hypotheses
about the genetic causes of autism spectrum
disorders and discovering treatments for the diagnostic symptoms of autism
, using mouse model
s. She has published more than 230 peer-reviewed
articles in scientific journals
and about 90 book chapters and review articles. According to the Web of Science
, her works have been cited over 16,000 times, giving her an h-index
of 72. She has co-edited 4 books and is the author of What's Wrong With my Mouse (2nd edition, ISBN 9780471471929), which was very well received.
. in biology
from the University of Pennsylvania
in 1971 and her PhD
in 1976 from the University of Maryland, College Park
. She then did postdoctoral research in neuropsychopharmacology at the Yale School of Medicine
(1976-1979).
-related and social behavior
in rodents, especially mice. Early in her career, she developed the dark-light mouse exploration test, and showed that it is a valid test for anxiety-like behaviors. More recently, she developed the three-compartment test to evaluate mouse social behavior.
(2000-2001) and the International Behavioural and Neural Genetics Society
(2008-2011). She is the editor-in-chief of Neuropeptides and serves on several editorial board
s, among them Autism Research, Genes, Brain and Behavior
, and Trends in Pharmacological Sciences
. In 2011, Crawley received the IBANGS Distinguished Investigator Award, which "recognizes the contributions of a senior scientist to the field, considering research, mentorship, and continued impact on the field".
Behavioral neuroscience
Behavioral neuroscience, also known as biological psychology, biopsychology, or psychobiology is the application of the principles of biology , to the study of physiological, genetic, and developmental mechanisms of behavior in human and non-human animals...
and an expert on rodent behavioral analysis. She currently is chief of the Laboratory of Behavioral Neuroscience in the intramural program of the National Institute of Mental Health
National Institute of Mental Health
The National Institute of Mental Health is one of 27 institutes and centers that make up the National Institutes of Health...
. Her translational research
Translational research
Translational research is a way of thinking about and conducting scientific research to make the results of research applicable to the population under study and is practised in the natural and biological, behavioural, and social sciences...
program focuses on testing hypotheses
Hypothesis
A hypothesis is a proposed explanation for a phenomenon. The term derives from the Greek, ὑποτιθέναι – hypotithenai meaning "to put under" or "to suppose". For a hypothesis to be put forward as a scientific hypothesis, the scientific method requires that one can test it...
about the genetic causes of autism spectrum
Autism spectrum
The term "autism spectrum" is often used to describe disorders that are currently classified as pervasive developmental disorders. Pervasive developmental disorders include autism, Asperger syndrome, Childhood disintegrative disorder, Rett syndrome and Pervasive Developmental Disorder Not Otherwise...
disorders and discovering treatments for the diagnostic symptoms of autism
Autism
Autism is a disorder of neural development characterized by impaired social interaction and communication, and by restricted and repetitive behavior. These signs all begin before a child is three years old. Autism affects information processing in the brain by altering how nerve cells and their...
, using mouse model
Animal testing on rodents
Rodents are commonly used in animal testing, particularly guinea pigs, hamsters, gerbils, rats, and mice.-The statistics:In the UK in 2004, 1,910,110 mice, 464,727 rats and 37,475 other rodents were used...
s. She has published more than 230 peer-reviewed
Peer review
Peer review is a process of self-regulation by a profession or a process of evaluation involving qualified individuals within the relevant field. Peer review methods are employed to maintain standards, improve performance and provide credibility...
articles in scientific journals
Scientific journal
In academic publishing, a scientific journal is a periodical publication intended to further the progress of science, usually by reporting new research. There are thousands of scientific journals in publication, and many more have been published at various points in the past...
and about 90 book chapters and review articles. According to the Web of Science
Web of Science
ISI Web of Knowledge is an academic citation indexing and search service, which is combined with web linking and provided by Thomson Reuters. Web of Knowledge coverage encompasses the sciences, social sciences, arts and humanities. It provides bibliographic content and the tools to access, analyze,...
, her works have been cited over 16,000 times, giving her an h-index
H-index
The h-index is an index that attempts to measure both the productivity and impact of the published work of a scientist or scholar. The index is based on the set of the scientist's most cited papers and the number of citations that they have received in other publications...
of 72. She has co-edited 4 books and is the author of What's Wrong With my Mouse (2nd edition, ISBN 9780471471929), which was very well received.
Education
Crawley obtained her B.ABachelor of Arts
A Bachelor of Arts , from the Latin artium baccalaureus, is a bachelor's degree awarded for an undergraduate course or program in either the liberal arts, the sciences, or both...
. in biology
Biology
Biology is a natural science concerned with the study of life and living organisms, including their structure, function, growth, origin, evolution, distribution, and taxonomy. Biology is a vast subject containing many subdivisions, topics, and disciplines...
from the University of Pennsylvania
University of Pennsylvania
The University of Pennsylvania is a private, Ivy League university located in Philadelphia, Pennsylvania, United States. Penn is the fourth-oldest institution of higher education in the United States,Penn is the fourth-oldest using the founding dates claimed by each institution...
in 1971 and her PhD
Doctor of Philosophy
Doctor of Philosophy, abbreviated as Ph.D., PhD, D.Phil., or DPhil , in English-speaking countries, is a postgraduate academic degree awarded by universities...
in 1976 from the University of Maryland, College Park
University of Maryland, College Park
The University of Maryland, College Park is a top-ranked public research university located in the city of College Park in Prince George's County, Maryland, just outside Washington, D.C...
. She then did postdoctoral research in neuropsychopharmacology at the Yale School of Medicine
Yale School of Medicine
The Yale School of Medicine at Yale University is a private medical school located in New Haven, Connecticut, U.S. It was founded in 1810 as The Medical Institution of Yale College, and formally opened its doors in 1813....
(1976-1979).
Behavioral test development
Crawley is at the origin of several widely-employed tests used to evaluate, for example, anxietyAnxiety
Anxiety is a psychological and physiological state characterized by somatic, emotional, cognitive, and behavioral components. The root meaning of the word anxiety is 'to vex or trouble'; in either presence or absence of psychological stress, anxiety can create feelings of fear, worry, uneasiness,...
-related and social behavior
Social behavior
In physics, physiology and sociology, social behavior is behavior directed towards society, or taking place between, members of the same species. Behavior such as predation which involves members of different species is not social...
in rodents, especially mice. Early in her career, she developed the dark-light mouse exploration test, and showed that it is a valid test for anxiety-like behaviors. More recently, she developed the three-compartment test to evaluate mouse social behavior.
Honors
Crawley has been president of the International Behavioral Neuroscience SocietyInternational Behavioral Neuroscience Society
The International Behavioral Neuroscience Society , was founded in 1992. The goal of the IBNS is to "encourage research and education in the field of behavioral neuroscience". Its current president is D. Caroline Blanchard...
(2000-2001) and the International Behavioural and Neural Genetics Society
International Behavioural and Neural Genetics Society
The International Behavioural and Neural Genetics Society was founded in 1996. The goal of IBANGS is "to promote the field of neurobehavioural genetics".- Mission :...
(2008-2011). She is the editor-in-chief of Neuropeptides and serves on several editorial board
Editorial board
The editorial board is a group of people, usually at a publication, who dictate the tone and direction the publication's editorial policy will take.- Board makeup :...
s, among them Autism Research, Genes, Brain and Behavior
Genes, Brain and Behavior
According to the Journal Citation Reports, its 2009 impact factor is 4.061, ranking Genes, Brain and Behavior 63rd out of 237 listed journals in the category "Neurosciences" and 6th out of 48 listed journals in the category "Behavioral Sciences"....
, and Trends in Pharmacological Sciences
Trends (journals)
Trends is a series of scientific journals owned by Elsevier that publish review articles in a range of areas of biology. They are currently part of Elsevier's Cell Press group of journals....
. In 2011, Crawley received the IBANGS Distinguished Investigator Award, which "recognizes the contributions of a senior scientist to the field, considering research, mentorship, and continued impact on the field".