Interleukin 1 receptor, type I
Encyclopedia
Interleukin 1 receptor, type I (IL1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor
. IL1R1 also denotes its human gene
.
with PIK3R1
, Myd88
and IL1RAP
.
Interleukin receptor
-Types:There are two main families of Interleukin receptors, type 1 and type 2 cytokine receptors.-Other:*Interleukin-1 receptor and interleukin-18 receptor belong to the immunoglobulin superfamily....
. IL1R1 also denotes its human gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
Interleukin 1 receptor, type I has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with PIK3R1
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene.-Interactions:PIK3R1 has been shown to interact with EPH receptor A2, KHDRBS1, Lymphocyte cytosolic protein 2, Janus kinase 2, GAB2, CD117, BCAR1, CD28, SHB, EZR, PIK3CD, GAB1, HRAS,...
, Myd88
Myd88
Myeloid differentiation primary response gene is a protein that, in humans, is encoded by the MYD88 gene.-Function:In mice, MyD88 is a universal adapter protein as it is used by all TLRs to activate the transcription factor NF-κB. Mal is necessary to recruit Myd88 to TLR 2 and TLR 4, and MyD88...
and IL1RAP
IL1RAP
Interleukin-1 receptor accessory protein is a protein that in humans is encoded by the IL1RAP gene.-Interactions:IL1RAP has been shown to interact with TOLLIP and Interleukin 1 receptor, type I.-Further reading:...
.