Imperatorin
Encyclopedia
Imperatorin is a furocoumarin
and a phytochemical
that has been isolated from Urena lobata L. (Malvaceae
), Angelica archangelica, Angelica dahurica
, Glehnia littoralis
, Saposhnikovia divaricata, Cnidium monnieri, Incarvillea younghusbandii, and Zanthoxylum americanum mill. It is biosynthesized from umbelliferone
, a coumarin
derivative.
with benzene
the air-dried and pulverised roots followed by separation by column chromatography
.
Furanocoumarin
Furanocoumarins, or furocoumarins, are a class of organic chemical compounds produced by a variety of plants. They are biosynthesized partly through the phenylpropanoid pathway and the mevalonate pathway, which is biosynthesized by a coupling of dimethylallyl pyrophosphate and 7-hydroxycoumarin...
and a phytochemical
Phytochemical
Phytochemicals are biologically active chemical compounds that occur naturally in plants . Phytochemicals are the molecules responsible for the color and organoleptic properties . For example, the deep purple color of blueberries and the smell of garlic...
that has been isolated from Urena lobata L. (Malvaceae
Malvaceae
Malvaceae, or the mallow family, is a family of flowering plants containing over 200 genera with close to 2,300 species. Judd & al. Well known members of this family include okra, jute and cacao...
), Angelica archangelica, Angelica dahurica
Angelica dahurica
Angelica dahurica is a wildy grown species of angelica native to Siberia, Russia Far East, Mongolia, Northeastern China, Japan, Korea, and Taiwan. This species tend to grow near river banks, along streams and among rocky shrubs. The root of the plant is widely used for its medicinal properties and...
, Glehnia littoralis
Glehnia littoralis
Glehnia littoralis is a species of plant in the "carrot family", Apiaceae, known by several common names including beach silvertop and American silvertop in English, and bei sha shen and shan hu cai in Chinese...
, Saposhnikovia divaricata, Cnidium monnieri, Incarvillea younghusbandii, and Zanthoxylum americanum mill. It is biosynthesized from umbelliferone
Umbelliferone
Umbelliferone, also known as 7-hydroxycoumarin, hydrangine, skimmetine, and beta-umbelliferone, is a widespread natural product of the coumarin family. It occurs in many familiar plants from the Apiaceae family such as carrot, coriander and garden angelica, as well plants from other families such...
, a coumarin
Coumarin
Coumarin is a fragrant chemical compound in the benzopyrone chemical class, found in many plants, notably in high concentration in the tonka bean , vanilla grass , sweet woodruff , mullein , sweet grass , cassia cinnamon and sweet clover...
derivative.
Isolation
The procedure for the isolation of imperatorin from Urena lobata involves exhaustively extracting under refluxReflux
Reflux is a technique involving the condensation of vapors and the return of this condensate to the system from which it originated. It is used in industrial and laboratory distillations...
with benzene
Benzene
Benzene is an organic chemical compound. It is composed of 6 carbon atoms in a ring, with 1 hydrogen atom attached to each carbon atom, with the molecular formula C6H6....
the air-dried and pulverised roots followed by separation by column chromatography
Column chromatography
Column chromatography in chemistry is a method used to purify individual chemical compounds from mixtures of compounds. It is often used for preparative applications on scales from micrograms up to kilograms.The main advantage of column chromatography is the relatively low cost and disposability...
.