IUCLID
Encyclopedia
IUCLID is a software application to capture, store, maintain and exchange data on intrinsic and hazard properties of chemical substance
s. Distributed free of charge, the software is especially useful to chemical industry companies and to government authorities. It is the key tool for chemical industry to fulfill data submission obligations under REACH
, a European Union
law covering the production and use of chemical substances. The software is maintained by the European Chemicals Agency
, ECHA. The latest version, version 5.3, was made available on 24 February 2011.
1999: IUCLID becomes the recommended tool for the OECD HPV Programme.
2000: IUCLID is the software prescribed in the EU Biocides legislation to notify existing active substances (Art. 4 of Commission Regulation (EC) No 1896/2000).
IUCLID 4 was used worldwide by about 500 organizations. These included chemical industry companies, EU
Member State Competent Authorities, the OECD Secretariat, the US EPA
, the Japan METI, and third party service providers.
, the European Commission
decided to completely overhaul IUCLID 4 and to create a new version, IUCLID 5, which would be used by chemical industry companies to fulfill their data submission obligations under REACH
. Migration of data in the IUCLID 4 format was supported by IUCLID 5.1. IUCLID 5.1 became available on 13 June 2007.
IUCLID is also mentioned in article 111 of the REACH of the REACH legislation as the format to be used for data collection and submission dossier preparation.
OECD and the European Commission have agreed on a standard XML
format (OECD Harmonized Templates) in which these data are stored for easy data sharing. IUCLID5 will be the first application fully implementing this international reporting standard, which has been accepted by many national and international regulatory authorities.
Numerous parties were involved in the creation and the review of the OECD Harmonized Templates, among them the Business and Industry Advisory Committee (BIAC) to the OECD, the European Chemical Industry Council (CEFIC) and other bodies and authorities.
In addition to dossier creation for REACH, IUCLID 5 data can be (re-)used for a large number of other purposes, due to the compatibility of IUCLID 5 data with the OECD Harmonized Templates. The European Commission
IUCLID project team and international authorities are currently in deliberation in order to further promote acceptance of IUCLID5 data in non-REACH
jurisdictions. Legislations and programmes under which IUCLID 5 data are certainly be accepted are:
The IUCLID 5 data model also features Biocide
s/Pesticide
s elements. A dataset prepared for a substance under REACH
can therefore be quickly complemented with data about possible biocidal or pesticidal properties and be re-used for data reporting obligations under the EU Biocides regulation
The data is available and can be searched through the OECD eChemPortal www.echemportal.org
based application, using the Hibernate
framework for persistence
. It features a Java Swing
graphical user interface (GUI)
and can be deployed on both single workstation and distributed environments.
IUCLID 5 offers the possibility to be deployed in:
Chemical substance
In chemistry, a chemical substance is a form of matter that has constant chemical composition and characteristic properties. It cannot be separated into components by physical separation methods, i.e. without breaking chemical bonds. They can be solids, liquids or gases.Chemical substances are...
s. Distributed free of charge, the software is especially useful to chemical industry companies and to government authorities. It is the key tool for chemical industry to fulfill data submission obligations under REACH
Registration, Evaluation and Authorisation of Chemicals
Registration, Evaluation, Authorisation and Restriction of Chemicals is a European Union Regulation of 18 December 2006. REACH addresses the production and use of chemical substances, and their potential impacts on both human health and the environment...
, a European Union
European Union
The European Union is an economic and political union of 27 independent member states which are located primarily in Europe. The EU traces its origins from the European Coal and Steel Community and the European Economic Community , formed by six countries in 1958...
law covering the production and use of chemical substances. The software is maintained by the European Chemicals Agency
European Chemicals Agency
The European Chemicals Agency is an agency of the European Union which manages the technical, scientific and administrative aspects of the Registration, Evaluation, Authorisation and Restriction of Chemicals system...
, ECHA. The latest version, version 5.3, was made available on 24 February 2011.
IUCLID versions 1 to 4
1993: First version of IUCLID for the European Existing Substances Regulation 793/93/EEC.1999: IUCLID becomes the recommended tool for the OECD HPV Programme.
2000: IUCLID is the software prescribed in the EU Biocides legislation to notify existing active substances (Art. 4 of Commission Regulation (EC) No 1896/2000).
IUCLID 4 was used worldwide by about 500 organizations. These included chemical industry companies, EU
European Union
The European Union is an economic and political union of 27 independent member states which are located primarily in Europe. The EU traces its origins from the European Coal and Steel Community and the European Economic Community , formed by six countries in 1958...
Member State Competent Authorities, the OECD Secretariat, the US EPA
United States Environmental Protection Agency
The U.S. Environmental Protection Agency is an agency of the federal government of the United States charged with protecting human health and the environment, by writing and enforcing regulations based on laws passed by Congress...
, the Japan METI, and third party service providers.
IUCLID 5
In 2003, when it became clear that the REACH proposal would be adopted by the European UnionEuropean Union
The European Union is an economic and political union of 27 independent member states which are located primarily in Europe. The EU traces its origins from the European Coal and Steel Community and the European Economic Community , formed by six countries in 1958...
, the European Commission
European Commission
The European Commission is the executive body of the European Union. The body is responsible for proposing legislation, implementing decisions, upholding the Union's treaties and the general day-to-day running of the Union....
decided to completely overhaul IUCLID 4 and to create a new version, IUCLID 5, which would be used by chemical industry companies to fulfill their data submission obligations under REACH
Registration, Evaluation and Authorisation of Chemicals
Registration, Evaluation, Authorisation and Restriction of Chemicals is a European Union Regulation of 18 December 2006. REACH addresses the production and use of chemical substances, and their potential impacts on both human health and the environment...
. Migration of data in the IUCLID 4 format was supported by IUCLID 5.1. IUCLID 5.1 became available on 13 June 2007.
IUCLID is also mentioned in article 111 of the REACH of the REACH legislation as the format to be used for data collection and submission dossier preparation.
Data Format and Exchange
Data that can be stored and maintained with IUCLID encompass information about:- The party running IUCLID (production sites, contact persons etc.)
- The chemical substances managed by the company, namely their
- composition,
- reference information like CASChemical Abstracts ServiceChemical Abstracts is a periodical index that provides summaries and indexes of disclosures in recently published scientific documents. Approximately 8,000 journals, technical reports, dissertations, conference proceedings, and new books, in any of 50 languages, are monitored yearly, as are patent...
number and other identifiers, - classification and labelling,
- physical/chemical properties,
- toxicologicalToxicologyToxicology is a branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals on living organisms...
properties, - eco-toxicologicalEcotoxicologyEcotoxicology is the study of the effects of toxic chemicals on biological organisms, especially at the population, community, ecosystem level. Ecotoxicology is a multidisciplinary field, which integrates toxicology and ecology....
properties.
OECD and the European Commission have agreed on a standard XML
XML
Extensible Markup Language is a set of rules for encoding documents in machine-readable form. It is defined in the XML 1.0 Specification produced by the W3C, and several other related specifications, all gratis open standards....
format (OECD Harmonized Templates) in which these data are stored for easy data sharing. IUCLID5 will be the first application fully implementing this international reporting standard, which has been accepted by many national and international regulatory authorities.
Numerous parties were involved in the creation and the review of the OECD Harmonized Templates, among them the Business and Industry Advisory Committee (BIAC) to the OECD, the European Chemical Industry Council (CEFIC) and other bodies and authorities.
Possible IUCLID 5 uses
Anyone can use a local IUCLID 5 installation to collect, store, maintain and exchange relevant data on chemical substances.In addition to dossier creation for REACH, IUCLID 5 data can be (re-)used for a large number of other purposes, due to the compatibility of IUCLID 5 data with the OECD Harmonized Templates. The European Commission
European Commission
The European Commission is the executive body of the European Union. The body is responsible for proposing legislation, implementing decisions, upholding the Union's treaties and the general day-to-day running of the Union....
IUCLID project team and international authorities are currently in deliberation in order to further promote acceptance of IUCLID5 data in non-REACH
Registration, Evaluation and Authorisation of Chemicals
Registration, Evaluation, Authorisation and Restriction of Chemicals is a European Union Regulation of 18 December 2006. REACH addresses the production and use of chemical substances, and their potential impacts on both human health and the environment...
jurisdictions. Legislations and programmes under which IUCLID 5 data are certainly be accepted are:
- [www.oecd.org/env/existingchemicals/ OECD Chemical Assessment Programme]
- US HPV Challenge Programme
- Japan HPV Challenge Programme(provided OECD guidance for SIDS dossiers is followed there).
The IUCLID 5 data model also features Biocide
Biocide
A biocide is a chemical substance or microorganism which can deter, render harmless, or exert a controlling effect on any harmful organism by chemical or biological means. Biocides are commonly used in medicine, agriculture, forestry, and industry...
s/Pesticide
Pesticide
Pesticides are substances or mixture of substances intended for preventing, destroying, repelling or mitigating any pest.A pesticide may be a chemical unicycle, biological agent , antimicrobial, disinfectant or device used against any pest...
s elements. A dataset prepared for a substance under REACH
Registration, Evaluation and Authorisation of Chemicals
Registration, Evaluation, Authorisation and Restriction of Chemicals is a European Union Regulation of 18 December 2006. REACH addresses the production and use of chemical substances, and their potential impacts on both human health and the environment...
can therefore be quickly complemented with data about possible biocidal or pesticidal properties and be re-used for data reporting obligations under the EU Biocides regulation
The data is available and can be searched through the OECD eChemPortal www.echemportal.org
IUCLID development and deployment
IUCLID 5 is a JavaJava (programming language)
Java is a programming language originally developed by James Gosling at Sun Microsystems and released in 1995 as a core component of Sun Microsystems' Java platform. The language derives much of its syntax from C and C++ but has a simpler object model and fewer low-level facilities...
based application, using the Hibernate
Hibernate (Java)
Hibernate is an object-relational mapping library for the Java language, providing a framework for mapping an object-oriented domain model to a traditional relational database...
framework for persistence
Persistence (computer science)
Persistence in computer science refers to the characteristic of state that outlives the process that created it. Without this capability, state would only exist in RAM, and would be lost when this RAM loses power, such as a computer shutdown....
. It features a Java Swing
Swing (Java)
Swing is the primary Java GUI widget toolkit. It is part of Oracle's Java Foundation Classes — an API for providing a graphical user interface for Java programs....
graphical user interface (GUI)
Graphical user interface
In computing, a graphical user interface is a type of user interface that allows users to interact with electronic devices with images rather than text commands. GUIs can be used in computers, hand-held devices such as MP3 players, portable media players or gaming devices, household appliances and...
and can be deployed on both single workstation and distributed environments.
IUCLID 5 offers the possibility to be deployed in:
- either a 100% open source system environment, using TomcatApache TomcatApache Tomcat is an open source web server and servlet container developed by the Apache Software Foundation...
as web containerWeb containerWeb container is the component of a web server that interacts with the servlets. A web container is responsible for managing the lifecycle of servlets, mapping a URL to a particular servlet and ensuring that the URL requester has the correct access rights...
and PostgreSQLPostgreSQLPostgreSQL, often simply Postgres, is an object-relational database management system available for many platforms including Linux, FreeBSD, Solaris, MS Windows and Mac OS X. It is released under the PostgreSQL License, which is an MIT-style license, and is thus free and open source software...
as Database Management System (DBMS)Database management systemA database management system is a software package with computer programs that control the creation, maintenance, and use of a database. It allows organizations to conveniently develop databases for various applications by database administrators and other specialists. A database is an integrated...
, - or a commercial system environment, using the Oracle WebLogic ServerOracle Weblogic ServerOwned by Oracle Corporation, Oracle WebLogic consists of a Java EE platform product-family that includes:* a Java EE application server, WebLogic Application Server* an enterprise portal, WebLogic Portal* an Enterprise Application Integration platform...
from Oracle CorporationOracle CorporationOracle Corporation is an American multinational computer technology corporation that specializes in developing and marketing hardware systems and enterprise software products – particularly database management systems...
as application serverApplication serverAn application server is a software framework that provides an environment in which applications can run, no matter what the applications are or what they do...
and/or OracleOracle databaseThe Oracle Database is an object-relational database management system produced and marketed by Oracle Corporation....
as Database Management System (DBMS)Database management systemA database management system is a software package with computer programs that control the creation, maintenance, and use of a database. It allows organizations to conveniently develop databases for various applications by database administrators and other specialists. A database is an integrated...
.
IUCLID system requirements
IUCLID can be deployed on any current PC. For optimal performance, RAM should not be less than 1 GB.See also
- Institute for Health and Consumer ProtectionInstitute for Health and Consumer ProtectionThe Institute for Health and Consumer Protection or IHCP, located in Ispra, Italy, is one of the seven institutes of the Joint Research Centre , a Directorate-General of the European Commission ....
- Joint Research Centre
- European CommissionEuropean CommissionThe European Commission is the executive body of the European Union. The body is responsible for proposing legislation, implementing decisions, upholding the Union's treaties and the general day-to-day running of the Union....
- REACHRegistration, Evaluation and Authorisation of ChemicalsRegistration, Evaluation, Authorisation and Restriction of Chemicals is a European Union Regulation of 18 December 2006. REACH addresses the production and use of chemical substances, and their potential impacts on both human health and the environment...
- OECD
External links
- IUCLID website
- European Chemicals Agency
- European Chemicals Bureau On-Line
- Institute for Health and Consumer Protection On-Line
- Joint Research Centre On-Line
- REACH Legislation Full text
- The REACH CD-ROM, a practical guide for REACH
- REACH Compliance
- PDF of IUCLID Installation Guide
- REACH Services Overview & Official REACH Texts
- eChemPortal, a global portal to information on Chemical Substances
- Data entry accelerator for IUCLID