Hippobroma longiflora
Encyclopedia
Hippobroma longiflora is a flowering plant in the Campanulaceae
Campanulaceae
The family Campanulaceae , of the order Asterales, contains about 2000 species in 70 genera of herbaceous plants, shrubs, and rarely small trees, often with milky non-toxic sap...

 family. It is endemic to the West Indies, but has become naturalized across the American tropics and Oceania
Oceania
Oceania is a region centered on the islands of the tropical Pacific Ocean. Conceptions of what constitutes Oceania range from the coral atolls and volcanic islands of the South Pacific to the entire insular region between Asia and the Americas, including Australasia and the Malay Archipelago...

.

It is notable for its concentrations of two pyridine
Pyridine
Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one C-H group replaced by a nitrogen atom...

 alkaloid
Alkaloid
Alkaloids are a group of naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids...

s: lobeline
Lobeline
Lobeline is a natural alkaloid found in "Indian tobacco" , "Devil's tobacco" , "cardinal flower" , "great lobelia" , and Hippobroma longiflora...

 and nicotine
Nicotine
Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6–3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves...

. The effects of nicotine and lobeline are quite similar, with psychoactive effects at small dosages and with unpleasant effects including vomiting, muscle paralysis, and trembling at higher dosages. For this reason, H. longiflora (and its various synonyms) is often referenced for both its toxicity and its ethnobotanical
Ethnobotany
Ethnobotany is the scientific study of the relationships that exist between people and plants....

uses.

When pulling this weed, it is important to wear gloves: the sap is an irritant which can be absorbed through the skin, and a small amount of sap in the eyes can cause blindness.
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