Hibernating myocardium
Encyclopedia
In cardiology
, hibernating myocardium is a state when some segments
of the myocardium exhibit abnormalities of contractile function. These
abnormalities can be visualised during echocardiography
or ventriculography. The finding of a perfusion or metabolic mismatch between PET-FDG and PET-NH3 is indicative of decreased metabolism. The wall of the affected segments is hypo-, a-, or dyskinetic.
The phenomenon is highly significant clinically because it usually manifests itself in the setting of chronic ischemia
, that is potentially reversible by revascularisation
via cardiac catheterization. The regions of myocardium are still viable and can restore its function. There develops a new steady state between myocardial blood flow (MBF) and myocardial function, MBF reduced and in consequence function is reduced too.
The clinical situations where one can expect hibernating myocardium are:
Cardiology
Cardiology is a medical specialty dealing with disorders of the heart . The field includes diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease and electrophysiology...
, hibernating myocardium is a state when some segments
of the myocardium exhibit abnormalities of contractile function. These
abnormalities can be visualised during echocardiography
Echocardiography
An echocardiogram, often referred to in the medical community as a cardiac ECHO or simply an ECHO, is a sonogram of the heart . Also known as a cardiac ultrasound, it uses standard ultrasound techniques to image two-dimensional slices of the heart...
or ventriculography. The finding of a perfusion or metabolic mismatch between PET-FDG and PET-NH3 is indicative of decreased metabolism. The wall of the affected segments is hypo-, a-, or dyskinetic.
The phenomenon is highly significant clinically because it usually manifests itself in the setting of chronic ischemia
Ischemia
In medicine, ischemia is a restriction in blood supply, generally due to factors in the blood vessels, with resultant damage or dysfunction of tissue. It may also be spelled ischaemia or ischæmia...
, that is potentially reversible by revascularisation
Revascularization
Revascularization is "a surgical procedure for the provision of a new, additional, or augmented blood supply to a body part or organ." The term derives from the prefix re-, in this case meaning "restoration" and vasculature, which refers to the circulatory structures of an organ.Revascularization...
via cardiac catheterization. The regions of myocardium are still viable and can restore its function. There develops a new steady state between myocardial blood flow (MBF) and myocardial function, MBF reduced and in consequence function is reduced too.
The clinical situations where one can expect hibernating myocardium are:
- chronic stable angina
- unstable angina
- silent ischemia
- after AMIMyocardial infarctionMyocardial infarction or acute myocardial infarction , commonly known as a heart attack, results from the interruption of blood supply to a part of the heart, causing heart cells to die...