Green Cross (japan)
Encyclopedia
Green Cross Corporation was one of the premier pharmaceutical companies
Pharmaceutical company
The pharmaceutical industry develops, produces, and markets drugs licensed for use as medications. Pharmaceutical companies are allowed to deal in generic and/or brand medications and medical devices...

 in Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...

. The company merged into Yoshitomi Pharmaceutical Co., Ltd. (吉富製薬株式会社) on April 1, 1998, and renamed to Welfide Corporation (ウェルファイド株式会社) on April 1, 2000. Finally Welfide Corp. and Mitsubishi-Tokyo Pharmaceutical Inc. (三菱東京製薬株式会社) were merged to form Mitsubishi Pharma Corporation (三菱ウェルファーマ株式会社) on October 1, 2001.

Green Cross was founded in 1950 as Japan's first commercial blood bank
Blood bank
A blood bank is a cache or bank of blood or blood components, gathered as a result of blood donation, stored and preserved for later use in blood transfusion. The term "blood bank" typically refers to a division of a hospital laboratory where the storage of blood product occurs and where proper...

 and became a diversified international pharmaceutical company producing ethical drugs for delivery or administration by doctors and healthcare workers. Its founders included war criminals such as Kitano Masaji
Masaji Kitano
Masaji Kitano was a medical doctor, microbiologist and the lieutenant general of the Imperial Japanese Army...

 who performed torture and experiments on humans in the Japanese military's notorious Unit 731
Unit 731
was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that undertook lethal human experimentation during the Second Sino-Japanese War and World War II. It was responsible for some of the most notorious war crimes carried out by Japanese...

 during World War II
World War II
World War II, or the Second World War , was a global conflict lasting from 1939 to 1945, involving most of the world's nations—including all of the great powers—eventually forming two opposing military alliances: the Allies and the Axis...

.

Its products were extensively used in the treatments of a wide range of ailments. As well as supplying whole blood for transfusions, Green Cross was also active in developing blood derivative products such as coagulation factors, immunoglobulin
Antibody
An antibody, also known as an immunoglobulin, is a large Y-shaped protein used by the immune system to identify and neutralize foreign objects such as bacteria and viruses. The antibody recognizes a unique part of the foreign target, termed an antigen...

 and albumin
Serum albumin
Serum albumin, often referred to simply as albumin is a protein that in humans is encoded by the ALB gene.Serum albumin is the most abundant plasma protein in mammals. Albumin is essential for maintaining the osmotic pressure needed for proper distribution of body fluids between intravascular...

. In the mid 1960s, it expanded into the non-plasma sector. Cardiovascular agents, coagulation/fibrinolytic agents, immunological agents, anti-inflammatory agents, albumin-based agents, blood plasma components and parenteral nutrition accounted for 71% of fiscal 1998 unconsolidated revenues; wholesale of diagnostic reagents, 14% and other, 15%. Unconsolidated revenues accounted for 59.5% of fiscal 1998 consolidated revenues. The company had eleven consolidated subsidiaries, three each in the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 and Japan, and one each in Germany
Germany
Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...

, the United Kingdom
United Kingdom
The United Kingdom of Great Britain and Northern IrelandIn the United Kingdom and Dependencies, other languages have been officially recognised as legitimate autochthonous languages under the European Charter for Regional or Minority Languages...

, Barbados
Barbados
Barbados is an island country in the Lesser Antilles. It is in length and as much as in width, amounting to . It is situated in the western area of the North Atlantic and 100 kilometres east of the Windward Islands and the Caribbean Sea; therein, it is about east of the islands of Saint...

, China
China
Chinese civilization may refer to:* China for more general discussion of the country.* Chinese culture* Greater China, the transnational community of ethnic Chinese.* History of China* Sinosphere, the area historically affected by Chinese culture...

 and Hong Kong
Hong Kong
Hong Kong is one of two Special Administrative Regions of the People's Republic of China , the other being Macau. A city-state situated on China's south coast and enclosed by the Pearl River Delta and South China Sea, it is renowned for its expansive skyline and deep natural harbour...

. Overseas sales accounted for 41.9% of fiscal 1998 consolidated revenues.

In the late 1980s, Green Cross and Takeshi Abe were at the center of a scandal
HIV-tainted blood scandal (Japan)
, refers to an event in the 1980s when between one and two thousand haemophilia patients in Japan contracted HIV via tainted blood products. Controversy centers on the continued use of non-heat-treated blood products after the development of heat-treatments that prevent the spread of infection...

 in which up to 3,000 Japanese contracted HIV
HIV
Human immunodeficiency virus is a lentivirus that causes acquired immunodeficiency syndrome , a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive...

through the distribution and use of blood products which were known to be unsafe.
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