Granule-cell-Purkinje-cell synapse
Encyclopedia
Granule-cell–Purkinje-cell synapses or gcPc synapses are the junctions that form the synapse
in the cerebellum
between granule cells and Purkinje cells. These synapses are thought to be a storage site for the information that is required for motor coordination
and their misfunctioning is involved with some movement disorder
s. Glutamate is the neurotransmitter
.
Synapse
In the nervous system, a synapse is a structure that permits a neuron to pass an electrical or chemical signal to another cell...
in the cerebellum
Cerebellum
The cerebellum is a region of the brain that plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language, and in regulating fear and pleasure responses, but its movement-related functions are the most solidly established...
between granule cells and Purkinje cells. These synapses are thought to be a storage site for the information that is required for motor coordination
Motor coordination
thumb|right|Motor coordination is shown in this animated sequence by [[Eadweard Muybridge]] of himself throwing a diskMotor coordination is the combination of body movements created with the kinematic and kinetic parameters that result in intended actions. Such movements usually smoothly and...
and their misfunctioning is involved with some movement disorder
Movement disorder
Movement disorders include:* Akathisia * Akinesia * Associated Movements * Athetosis...
s. Glutamate is the neurotransmitter
Neurotransmitter
Neurotransmitters are endogenous chemicals that transmit signals from a neuron to a target cell across a synapse. Neurotransmitters are packaged into synaptic vesicles clustered beneath the membrane on the presynaptic side of a synapse, and are released into the synaptic cleft, where they bind to...
.