Gabriel-Colman rearrangement
Encyclopedia
The Gabriel-Colman rearrangement is the chemical reaction
of phthalimidoacetic esters (2) with strong base to form substituted isoquinoline
s (3).
Chemical reaction
A chemical reaction is a process that leads to the transformation of one set of chemical substances to another. Chemical reactions can be either spontaneous, requiring no input of energy, or non-spontaneous, typically following the input of some type of energy, such as heat, light or electricity...
of phthalimidoacetic esters (2) with strong base to form substituted isoquinoline
Isoquinoline
Isoquinoline is a heterocyclic aromatic organic compound. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. In a broader sense, the term isoquinoline is used to make reference to isoquinoline...
s (3).