GPHN
Encyclopedia
GPHN is a human gene
that encodes the protein
gephyrin
.
with Mammalian target of rapamycin
and ARHGEF9
.
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
that encodes the protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
gephyrin
Gephyrin
Gephyrin is a protein that is a component of the postsynaptic protein network of inhibitory synapses. Positive antibody staining for gephyrin at a synapse is consistent with the presence of glycine and/or GABA-A receptors. Gephyrin displaces GABA receptors from the GABARAP/P130 complex, then brings...
.
Interactions
GPHN has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Mammalian target of rapamycin
Mammalian target of rapamycin
The mammalian target of rapamycin also known as mechanistic target of rapamycin or FK506 binding protein 12-rapamycin associated protein 1 is a protein which in humans is encoded by the FRAP1 gene...
and ARHGEF9
ARHGEF9
Rho guanine nucleotide exchange factor 9 is a protein that in humans is encoded by the ARHGEF9 gene.-Interactions:ARHGEF9 has been shown to interact with GPHN and SMURF1.-Further reading:...
.