GLO1
Encyclopedia
Lactoylglutathione lyase is an enzyme
that in humans is encoded by the GLO1 gene
. It is a Lactoylglutathione lyase
.
Recent research demonstrates that GLO1 expression is upregulated in various human malignant tumors including metastatic melanoma.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the GLO1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. It is a Lactoylglutathione lyase
Lactoylglutathione lyase
In enzymology, a lactoylglutathione lyase is an enzyme that catalyzes the isomerization of hemithioacetal adducts, which are formed in a spontaneous reaction between a glutathionyl group and aldehydes such as methylglyoxal.The systematic name of this enzyme class is -S-lactoylglutathione...
.
Recent research demonstrates that GLO1 expression is upregulated in various human malignant tumors including metastatic melanoma.