Friedrich Ernst Krukenberg
Encyclopedia
Friedrich Ernst Krukenberg (April 1, 1871 - February 20, 1946) was a German physician who was a native of Halle an der Saale. He was a brother to orthopedic surgeon Hermann Krukenberg
(1863-1935), and Georg Heinrich Peter Krukenberg (1856-1899), who was a professor of gynecology at the University of Bonn
.
Krukenberg originally studied in his native city of Halle, and continued his medical education at the University of Marburg, where he was a student of ophthalmologist Theodor Axenfeld
(1867-1930). At Marburg
he also studied under pathologist Felix Jacob Marchand
(1846-1928), in whose department he described a fibrosarcoma
of the ovary
that was to become known as a Krukenberg tumor
. In 1896 he published his findings in an article called Über das Fibrosarcoma ovarii mucocellulare (carcinomatodes).
Later, his interest turned to ophthalmology
, and eventually he returned to Halle where he opened a private practice. The ophthalmic term "Krukenberg's spindle" is named after him, which is a vertical, fusiform deposition of melanin
pigmentation in the deep layers of the cornea
.
Hermann Krukenberg
Hermann Krukenberg was a German surgeon who was a native of Calbe, Province of Saxony, Germany. He was the brother of pathologist Friedrich Ernst Krukenberg ....
(1863-1935), and Georg Heinrich Peter Krukenberg (1856-1899), who was a professor of gynecology at the University of Bonn
University of Bonn
The University of Bonn is a public research university located in Bonn, Germany. Founded in its present form in 1818, as the linear successor of earlier academic institutions, the University of Bonn is today one of the leading universities in Germany. The University of Bonn offers a large number...
.
Krukenberg originally studied in his native city of Halle, and continued his medical education at the University of Marburg, where he was a student of ophthalmologist Theodor Axenfeld
Theodor Axenfeld
Karl Theodor Paul Polykarpus Axenfeld was a German ophthalmologist who was born in Smyrna in the Ottoman Empire to a German minister. As a child his family moved back to Germany in the town of Godesberg. He received his medical doctorate in 1890 from the University of Marburg...
(1867-1930). At Marburg
Marburg
Marburg is a city in the state of Hesse, Germany, on the River Lahn. It is the main town of the Marburg-Biedenkopf district and its population, as of March 2010, was 79,911.- Founding and early history :...
he also studied under pathologist Felix Jacob Marchand
Felix Jacob Marchand
Felix Jacob Marchand was a German pathologist who was born in Halle an der Saale. He studied medicine in Berlin, and later became an assistant at the pathological institute in Halle. In 1881 he became a professor of pathological anatomy in Giessen, and two years later garnered the same position at...
(1846-1928), in whose department he described a fibrosarcoma
Fibrosarcoma
Fibrosarcoma is a malignant tumor derived from fibrous connective tissue and characterized by immature proliferating fibroblasts or undifferentiated anaplastic spindle cells.Usually in males ages 30 to 40. Originates in fibrous tissues of the bone. Invades long or flat bones such as femur, tibia,...
of the ovary
Ovary
The ovary is an ovum-producing reproductive organ, often found in pairs as part of the vertebrate female reproductive system. Ovaries in anatomically female individuals are analogous to testes in anatomically male individuals, in that they are both gonads and endocrine glands.-Human anatomy:Ovaries...
that was to become known as a Krukenberg tumor
Krukenberg tumor
A Krukenberg tumor refers to a malignancy in the ovary that metastasized from a primary site, classically the gastrointestinal tract, although it can arise in other tissues such as the breast. Gastric adenocarcinoma, especially at the pylorus, is the most common source...
. In 1896 he published his findings in an article called Über das Fibrosarcoma ovarii mucocellulare (carcinomatodes).
Later, his interest turned to ophthalmology
Ophthalmology
Ophthalmology is the branch of medicine that deals with the anatomy, physiology and diseases of the eye. An ophthalmologist is a specialist in medical and surgical eye problems...
, and eventually he returned to Halle where he opened a private practice. The ophthalmic term "Krukenberg's spindle" is named after him, which is a vertical, fusiform deposition of melanin
Melanin
Melanin is a pigment that is ubiquitous in nature, being found in most organisms . In animals melanin pigments are derivatives of the amino acid tyrosine. The most common form of biological melanin is eumelanin, a brown-black polymer of dihydroxyindole carboxylic acids, and their reduced forms...
pigmentation in the deep layers of the cornea
Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, with the cornea accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is...
.