Formiminoglutamic acid
Encyclopedia
Formiminoglutamic acid is an intermediate in the metabolism of histidine
.
The "FIGLU" test is used to identify deficiency of vitamin B12
or folate deficiency
or liver disease
.
Histidine
Histidine Histidine, an essential amino acid, has a positively charged imidazole functional group. It is one of the 22 proteinogenic amino acids. Its codons are CAU and CAC. Histidine was first isolated by German physician Albrecht Kossel in 1896. Histidine is an essential amino acid in humans...
.
The "FIGLU" test is used to identify deficiency of vitamin B12
Vitamin B12
Vitamin B12, vitamin B12 or vitamin B-12, also called cobalamin, is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins...
or folate deficiency
Folate deficiency
Folate deficiency is a lack of folic acid in the diet and the signs are often subtle. Folate deficiency anemia is the medical name given for the condition. -Symptoms:Loss of appetite, and weight loss can occur...
or liver disease
Liver disease
Liver disease is a broad term describing any single number of diseases affecting the liver.-Diseases:* Hepatitis, inflammation of the liver, caused mainly by various viruses but also by some poisons , autoimmunity or hereditary conditions...
.
See also
- Imidazol-4-one-5-propionic acidImidazol-4-one-5-propionic acidImidazol-4-one-5-propionic acid is an intermediate in the metabolism of histidine.-See also:* Urocanate hydratase* Urocanate* Formiminoglutamic acid...
- Glutamate-1-semialdehydeGlutamate-1-semialdehydeThis file may be error. The precursor to ornithine and proline is thought to be glutamate-5-semialdehyde. See, for instance, Thomas M. Devlin, Textbook of Biochemistry with Clinical Correlations, Sixth Edition, p. 755 and p. 756 .Glutamate-1-semialdehyde is a molecule formed from...
- Formiminotransferase cyclodeaminaseFormiminotransferase cyclodeaminaseFormiminotransferase cyclodeaminase is an enzyme that catalyzes the conversion of formiminoglutamate and tetrahydrofolate into formiminotetrahydrofolate and glutamate....
- Glutamic acidGlutamic acidGlutamic acid is one of the 20 proteinogenic amino acids, and its codons are GAA and GAG. It is a non-essential amino acid. The carboxylate anions and salts of glutamic acid are known as glutamates...