Evotec
Encyclopedia
Evotec AG is a drug discovery alliance and development partnership company focused on progressing product approaches with leading pharmaceutical and biotechnology companies.

The company`s headquarters are located in Hamburg
Hamburg
-History:The first historic name for the city was, according to Claudius Ptolemy's reports, Treva.But the city takes its modern name, Hamburg, from the first permanent building on the site, a castle whose construction was ordered by the Emperor Charlemagne in AD 808...

, Germany. Evotec operates worldwide and is providing integrated drug discovery solutions, covering all activities from target-to-clinic.

Evotec employs more than 500 scientists and is working with integrated technologies in key therapeutic areas including neurodegenerative diseases e.g Alzheimer disease, pain
Pain
Pain is an unpleasant sensation often caused by intense or damaging stimuli such as stubbing a toe, burning a finger, putting iodine on a cut, and bumping the "funny bone."...

, metabolic diseases, e.g. diabetes, as well as oncology
Oncology
Oncology is a branch of medicine that deals with cancer...

 and inflammation
Inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...

. The company has long-term discovery alliances with partners including Boehringer Ingelheim, CHDI, Genentech
Genentech
Genentech Inc., or Genetic Engineering Technology, Inc., is a biotechnology corporation, founded in 1976 by venture capitalist Robert A. Swanson and biochemist Dr. Herbert Boyer. Trailing the founding of Cetus by five years, it was an important step in the evolution of the biotechnology industry...

, Medimmune/Astra Zeneca, Ono Pharmaceutical and UCB. In addition, the Company has existing development partnerships with pharmaceutical companies like Roche
Roche
Roche is French for "boulder/rock". The word is several names:-Business & companies:* Hoffmann–La Roche AG, Basel, Switzerland, one of the largest pharmaceutical companies in the world....

 also has product candidates both in clinical and preclinical development including EVT 103, P2X3 and H3. In the fiscal year 2010 Evotec generated revenues of € 55,3 m and has 608 employees (06/ 2011).

Since 28 October 2009 the company is listed in the TecDAX
TecDAX
The TecDAX stock index tracks the performance of the 30 largest German companies from the technology sector. In terms of order book turnover and market capitalization the companies rank below those included in the DAX.The TecDax was introduced on 24 March 2003...

 index.

History

Evotec BioSystems GmbH was founded in Hamburg, Germany in 1993. Among the founders were Nobel Laureate Professor Manfred Eigen
Manfred Eigen
Manfred Eigen is a German biophysical chemist who won the 1967 Nobel Prize in Chemistry for work on measuring fast chemical reactions.-Career:...

, Dr Karsten Henco, Dr Ulrich Aldag, Dr Freimut Leidenberger, Dr Heinrich Schulte, Professor Rudolf Rigler and Dr Charles Weissmann.

In the first years the company establishes collaborations with international pharma companies like Novartis and SmithKlineBeecham to develop a High-Throughput Screening System (EVOscreen®). In 1999 Evotec Biosystems goes public (Frankfurt Stock Exchange: EVT) and merges one year later with the british company Oxford Asymmetry International plc, which offers chemical services for biotech and pharma companies and forms Evotec OAI (in 2005 the name changes to Evotec AG).

In 2002 the company is divided into two business parts, namely “Discovery and Development Services“ and “Tools and Technologies“. In this year Evotec Technologies GmbH is founded.

In 2006 Evotec Technologies is sold to Perkin Elmer, to focus on its core business, the discovery and development of new pharmaceutical drugs. In 2008 Evotec acquires Renovis, an US biotech company and is listed on Nasdaq
NASDAQ
The NASDAQ Stock Market, also known as the NASDAQ, is an American stock exchange. "NASDAQ" originally stood for "National Association of Securities Dealers Automated Quotations". It is the second-largest stock exchange by market capitalization in the world, after the New York Stock Exchange. As of...

. One year later Evotec voluntarily delists its American Depository Shares from the NASDAQ stock market to concentrate its share trading on re-entered TecDAX
TecDAX
The TecDAX stock index tracks the performance of the 30 largest German companies from the technology sector. In terms of order book turnover and market capitalization the companies rank below those included in the DAX.The TecDax was introduced on 24 March 2003...

platform and reduces associated costs. Additionally Evotec takes over 70% of indian Research Support International Limited (RSIPL), a company providing organic synthesis and a zebrafish screening-platform from Summit Corporation.

In 2010 the company acquires DeveloGen AG, a company focused on novel therapies for metabolic disorders, e.g. diabetes. In 2011 Evotec acquires two companies; Kinaxo Biotechnologies GmbH, a Munich based, privately owned biotech company. Kinaxo's capabilities comprise a combination of technologies improving drug development across the entire pharma value chain. Furthermore Evotec takes over the compound management business from Biofocus, a subsidiary of the Galapagos group.

Alliances&Projects

Drug discovery alliances
  • Boehringer Ingelheim (oncology, pain, inflammation, metabolics, insulin sensitizers)
  • CHDI (CNS, Huntington disease)
  • Cubist
  • Genentech
    Genentech
    Genentech Inc., or Genetic Engineering Technology, Inc., is a biotechnology corporation, founded in 1976 by venture capitalist Robert A. Swanson and biochemist Dr. Herbert Boyer. Trailing the founding of Cetus by five years, it was an important step in the evolution of the biotechnology industry...

     (CNS, pain)
  • Medimmune/ Astra Zenenca (Beta cell technology; Biologicals)
  • Novartis
    Novartis
    Novartis International AG is a multinational pharmaceutical company based in Basel, Switzerland, ranking number three in sales among the world-wide industry...

     (CNS, pain)
  • Ono
  • Roche
    Roche
    Roche is French for "boulder/rock". The word is several names:-Business & companies:* Hoffmann–La Roche AG, Basel, Switzerland, one of the largest pharmaceutical companies in the world....

     (Response prediction)
  • Shionogi
  • UCB (CNS)
  • Vifor(Anemia)
  • Pfizer
    Pfizer
    Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States...

     (CNS)


Development partnerships
  • Teva/ Androm
  • JingXin
  • Boehringer Ingelheim
  • Pfizer
    Pfizer
    Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States...

  • Roche
    Roche
    Roche is French for "boulder/rock". The word is several names:-Business & companies:* Hoffmann–La Roche AG, Basel, Switzerland, one of the largest pharmaceutical companies in the world....



Technology Partners
  • Chem Bridge Corporation
  • Diamond Light Source
  • DiscoveRx
  • Hypha Discovery
  • PsychoGenics Inc.

Locations

Germany
Germany
Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...

, Hamburg
Hamburg
-History:The first historic name for the city was, according to Claudius Ptolemy's reports, Treva.But the city takes its modern name, Hamburg, from the first permanent building on the site, a castle whose construction was ordered by the Emperor Charlemagne in AD 808...

 (Headquarters), Berlin
Berlin
Berlin is the capital city of Germany and is one of the 16 states of Germany. With a population of 3.45 million people, Berlin is Germany's largest city. It is the second most populous city proper and the seventh most populous urban area in the European Union...

 & Goettingen
  • Screening
  • HTS (High-Throuput-Screening)
  • NMR (nuclear magnetic resonance)
  • in vitro & in vivo biology


Munich
Munich
Munich The city's motto is "" . Before 2006, it was "Weltstadt mit Herz" . Its native name, , is derived from the Old High German Munichen, meaning "by the monks' place". The city's name derives from the monks of the Benedictine order who founded the city; hence the monk depicted on the city's coat...

, Martinsried
Martinsried
Martinsried is a section of Planegg, a municipality neighboring Munich, Germany. Martinsried lies about 15 km southwest of Munich's city center.Martinsried is mostly known as the location of the Max Planck Institute of Biochemistry and the...

  • Phosphoproteomics
  • Chemical proteomics


USA, San Francisco
  • Compound Procurement
  • Compound QC and storage


India
India
India , officially the Republic of India , is a country in South Asia. It is the seventh-largest country by geographical area, the second-most populous country with over 1.2 billion people, and the most populous democracy in the world...

, Thane
Thane
Thane , is a city in Maharashtra, India, part of the Mumbai Metropolitan Region, northeastern suburb of Mumbai at the head of the Thane Creek. It is the administrative headquarters of Thane district. On 16 April 1853, G.I.P...

  • Library synthesis & management
  • Medicinal chemistry support
  • Development chemistry


UK, Abingdon
Abingdon
Abingdon may refer to the following places:In Australia :* Abingdon, Queensland, a place in Northern QueenslandIn Britain:*Abingdon, Oxfordshire**Abingdon School**Abingdon Abbey**Abingdon Lock**Abingdon Bridge**Abingdon Air & Country Show...

  • Medicinal chemistry
  • Zebrafish screening
  • ADMET
  • Structural biology

Management and Supervisory Board

Management
  • Dr Werner Lanthaler (Vorsitzender, Chief Executive Officer)
  • Colin Bond (Finanzen, Chief Financial Officer)
  • Dr Cord Dohrmann (Chief Scientific Officer)
  • Dr Mario Polywka (Chief Operating Officer)
  • Dr Klaus Maleck (Executive Vice President Corporate Development)


Supervisory Board
  • Dr Flemming Oernskov (Chairman)
  • Dr Walter Wenninger
  • Dr Hubert Birner
  • Roland Oetker
  • Prof Dr Andreas Pinkwart
  • Mary C. Tanner
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