Ethyl diazoacetate
Encyclopedia
Ethyl diazoacetate is a diazo
compound and a reagent in organic chemistry
. It was discovered by Theodor Curtius
in 1883. The compound can be prepared by reaction of the ethyl
ester
of glycine
with sodium nitrite
and sodium acetate
in water.
It is used in the cyclopropanation of alkenes.
Although the compound is hazardous it is used in chemical industry. Procedures for safe industrial handling have been published
Diazo
Diazo refers to a type of organic compound called diazo compound that has two linked nitrogen atoms as a terminal functional group. The general formula is R2C=N2. The simplest example of a diazo compound is diazomethane...
compound and a reagent in organic chemistry
Organic chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, composition, reactions, and preparation of carbon-based compounds, hydrocarbons, and their derivatives...
. It was discovered by Theodor Curtius
Theodor Curtius
- External links :* * * *...
in 1883. The compound can be prepared by reaction of the ethyl
Ethyl
Ethyl may refer to:* Ethyl group, a functional group in organic chemistry* Ethyl Corporation, a fuel additive company* Ethanol, also known as ethyl alcohol* Cold Ethyl, a rock band founded by Nicke Andersson...
ester
Ester
Esters are chemical compounds derived by reacting an oxoacid with a hydroxyl compound such as an alcohol or phenol. Esters are usually derived from an inorganic acid or organic acid in which at least one -OH group is replaced by an -O-alkyl group, and most commonly from carboxylic acids and...
of glycine
Glycine
Glycine is an organic compound with the formula NH2CH2COOH. Having a hydrogen substituent as its 'side chain', glycine is the smallest of the 20 amino acids commonly found in proteins. Its codons are GGU, GGC, GGA, GGG cf. the genetic code.Glycine is a colourless, sweet-tasting crystalline solid...
with sodium nitrite
Sodium nitrite
Sodium nitrite is the inorganic compound with the chemical formula NaNO2. It is a white to slight yellowish crystalline powder that is very soluble in water and is hygroscopic...
and sodium acetate
Sodium acetate
Sodium acetate, CH3COONa, also abbreviated NaOAc, also sodium ethanoate, is the sodium salt of acetic acid. This colourless salt has a wide range of uses.-Industrial:...
in water.
It is used in the cyclopropanation of alkenes.
Although the compound is hazardous it is used in chemical industry. Procedures for safe industrial handling have been published