Endcapping
Encyclopedia
Endcapping refers in chromatography
to the replacement of accessible silanol
groups in a bonded stationary phase by trimethylsilyl
groups.
Endcapping technology prevents the tailing of a polar compound
's peak and shows very high durability even with an alkaline mobile phase because of the strong film covering the stationary phase surface.
Chromatography
Chromatography is the collective term for a set of laboratory techniques for the separation of mixtures....
to the replacement of accessible silanol
Silanol
Silanol, also known as silyl alcohol, is a chemical with formula SiH3OH. It is the simplest silicon alcohol, and is a heavy, volatile, colorless, flammable liquid. At room temperature it is a polar liquid...
groups in a bonded stationary phase by trimethylsilyl
Trimethylsilyl
A trimethylsilyl group is a functional group in organic chemistry. This group consists of three methyl groups bonded to a silicon atom [−Si3], which is in turn bonded to the rest of a molecule...
groups.
Endcapping technology prevents the tailing of a polar compound
Chemical compound
A chemical compound is a pure chemical substance consisting of two or more different chemical elements that can be separated into simpler substances by chemical reactions. Chemical compounds have a unique and defined chemical structure; they consist of a fixed ratio of atoms that are held together...
's peak and shows very high durability even with an alkaline mobile phase because of the strong film covering the stationary phase surface.