Elkhonon Goldberg
Encyclopedia
Elkhonon Goldberg is a neuropsychologist and cognitive neuroscientist known for his work in hemispheric specialization
and the "novelty-routinization" theory.
with the great neuropsychologist Alexander Luria
and moved to the United States in 1974. He is currently a Clinical Professor of Neurology at New York University School of Medicine, Diplomate of The American Board of Professional Psychology in Clinical Neuropsychology, and Co-Founder and Chief Scientific Advisor of SharpBrains, an online brain fitness center. He offers post-doctoral training in Neuropsychology at Fielding Graduate University
.
, memory
, cognitive aging, and general theory of functional cortical organization.
Among the early critics of the fashionable notion of neocortical modularity, he introduced the notion of "cognitive gradient" to capture the distributed and emergent properties of functional cortical organization.
Goldberg's work on frontal lobe functions includes the discovery of the "reticulo-frontal disconnection" syndrome, functional lateralization and gender differences in the prefrontal cortex
. His work on memory includes the description of relatively pure retrograde amnesia
without anterograde amnesia
, which in turn has led to the elucidation of the role of brain stem
arousal
mechanisms in memory.
In clinical practice, Goldberg was among the early proponents of "cognitive fitness," purporting to harness the effects of life-long neuroplasticity
to delay and even reverse the effects of cognitive aging. First introduced by Michael Merzenich
, the concept has gained the support of a number of leading neuroscientists. Nonetheless, it remains controversial and further research is required to validate it.
Goldberg is an author of a number of scientific journal articles and book chapters, as well as of three books: Contemporary Neuropsychology and the Legacy of Luria; The Executive Brain: Frontal Lobes and the Civilized Mind; and The Wisdom Paradox: How Your Mind Can Grow Stronger As Your Brain Grows Older.
Specifically, the right hemisphere favors the "heteromodal association cortex" while the left favors the "modality-specific association cortex", and both are engaged in complex information processing. The latter deals solely with processing information arriving from individual sensory systems, such as visual, auditory, and sensory ones. This kind of cortex, favoring more local connections between adjacent cortical regions, "dismantles the world around us to separate representations. ... think of an object in a three-dimensional space projected onto the x, y, z coordinates
...". On the other hand, the heteromodal association cortex, favoring distant inter-cortical connections, integrates information arriving from sensory channels, or puts "the synthetic picture of the multimedia world around us back together." Goldberg likens these differences in connectivity thus: the left hemisphere is like a fleet of taxicabs that traverses short town-like distances while the right is like a fleet of airplanes that traverses large continental distances.
The novelty-routinization theory incorporates the more traditional distinction between verbal and nonverbal functions as a special case, but is more dynamic in nature, allows for evolutionary continuities, and provides a neurodevelopmental framework.
Lateralization of brain function
A longitudinal fissure separates the human brain into two distinct cerebral hemispheres, connected by the corpus callosum. The sides resemble each other and each hemisphere's structure is generally mirrored by the other side. Yet despite the strong anatomical similarities, the functions of each...
and the "novelty-routinization" theory.
Biography
Goldberg studied at Moscow State UniversityMoscow State University
Lomonosov Moscow State University , previously known as Lomonosov University or MSU , is the largest university in Russia. Founded in 1755, it also claims to be one of the oldest university in Russia and to have the tallest educational building in the world. Its current rector is Viktor Sadovnichiy...
with the great neuropsychologist Alexander Luria
Alexander Luria
Alexander Romanovich Luria was a famous Soviet neuropsychologist and developmental psychologist. He was one of the founders of neuropsychology and the jointly led the Vygotsky Circle.- Biography :...
and moved to the United States in 1974. He is currently a Clinical Professor of Neurology at New York University School of Medicine, Diplomate of The American Board of Professional Psychology in Clinical Neuropsychology, and Co-Founder and Chief Scientific Advisor of SharpBrains, an online brain fitness center. He offers post-doctoral training in Neuropsychology at Fielding Graduate University
Fielding Graduate University
Fielding Graduate University, previously Fielding Graduate Institute, and The Fielding Institute, is an accredited, nonprofit post-graduate institution of higher learning based in Santa Barbara, California, USA....
.
Scientific work
At Moscow State University, Goldberg studied psychology and mathematics and was among the early proponents of the discipline known today as computational neuroscience. In the United States Goldberg's work has been more clinical in nature. His research has focused on the function of the frontal lobes, hemispheric specializationLateralization of brain function
A longitudinal fissure separates the human brain into two distinct cerebral hemispheres, connected by the corpus callosum. The sides resemble each other and each hemisphere's structure is generally mirrored by the other side. Yet despite the strong anatomical similarities, the functions of each...
, memory
Memory
In psychology, memory is an organism's ability to store, retain, and recall information and experiences. Traditional studies of memory began in the fields of philosophy, including techniques of artificially enhancing memory....
, cognitive aging, and general theory of functional cortical organization.
Among the early critics of the fashionable notion of neocortical modularity, he introduced the notion of "cognitive gradient" to capture the distributed and emergent properties of functional cortical organization.
Goldberg's work on frontal lobe functions includes the discovery of the "reticulo-frontal disconnection" syndrome, functional lateralization and gender differences in the prefrontal cortex
Prefrontal cortex
The prefrontal cortex is the anterior part of the frontal lobes of the brain, lying in front of the motor and premotor areas.This brain region has been implicated in planning complex cognitive behaviors, personality expression, decision making and moderating correct social behavior...
. His work on memory includes the description of relatively pure retrograde amnesia
Retrograde amnesia
Retrograde amnesia is a loss of access to events that occurred, or information that was learned, before an injury or the onset of a disease....
without anterograde amnesia
Anterograde amnesia
Anterograde amnesia is a loss of the ability to create new memories after the event that caused the amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact. This is in contrast to retrograde amnesia, where memories...
, which in turn has led to the elucidation of the role of brain stem
Brain stem
In vertebrate anatomy the brainstem is the posterior part of the brain, adjoining and structurally continuous with the spinal cord. The brain stem provides the main motor and sensory innervation to the face and neck via the cranial nerves...
arousal
Arousal
Arousal is a physiological and psychological state of being awake or reactive to stimuli. It involves the activation of the reticular activating system in the brain stem, the autonomic nervous system and the endocrine system, leading to increased heart rate and blood pressure and a condition of...
mechanisms in memory.
In clinical practice, Goldberg was among the early proponents of "cognitive fitness," purporting to harness the effects of life-long neuroplasticity
Neuroplasticity
Neuroplasticity is a non-specific neuroscience term referring to the ability of the brain and nervous system in all species to change structurally and functionally as a result of input from the environment. Plasticity occurs on a variety of levels, ranging from cellular changes involved in...
to delay and even reverse the effects of cognitive aging. First introduced by Michael Merzenich
Michael Merzenich
Michael M. Merzenich is a professor emeritus neuroscientist at the University of California, San Francisco. His contributions to the field are numerous. He took the sensory cortex maps developed by his predecessors like Archie Tunturi, Clinton Woolsey, Vernon Mountcastle, Wade Marshall, and Philip...
, the concept has gained the support of a number of leading neuroscientists. Nonetheless, it remains controversial and further research is required to validate it.
Goldberg is an author of a number of scientific journal articles and book chapters, as well as of three books: Contemporary Neuropsychology and the Legacy of Luria; The Executive Brain: Frontal Lobes and the Civilized Mind; and The Wisdom Paradox: How Your Mind Can Grow Stronger As Your Brain Grows Older.
Novelty-routinization theory
His work on hemispheric specialization culminated in the "novelty-routinization" theory positing that (for the predominantly right-handed population) the two cerebral hemispheres are differentially involved in processing novel, unknown information (the right hemisphere) and processing in terms of stable pattern-recognition devices for known situations of mental routine (the left hemisphere). As for left-handers and ambidextrals, Goldberg indicates that the two hemispheres are less differentiated in function and structure. For these individuals there may be instances in which the left hemisphere takes the role of novelty processing and the right the routine processing.Specifically, the right hemisphere favors the "heteromodal association cortex" while the left favors the "modality-specific association cortex", and both are engaged in complex information processing. The latter deals solely with processing information arriving from individual sensory systems, such as visual, auditory, and sensory ones. This kind of cortex, favoring more local connections between adjacent cortical regions, "dismantles the world around us to separate representations. ... think of an object in a three-dimensional space projected onto the x, y, z coordinates
Cartesian coordinate system
A Cartesian coordinate system specifies each point uniquely in a plane by a pair of numerical coordinates, which are the signed distances from the point to two fixed perpendicular directed lines, measured in the same unit of length...
...". On the other hand, the heteromodal association cortex, favoring distant inter-cortical connections, integrates information arriving from sensory channels, or puts "the synthetic picture of the multimedia world around us back together." Goldberg likens these differences in connectivity thus: the left hemisphere is like a fleet of taxicabs that traverses short town-like distances while the right is like a fleet of airplanes that traverses large continental distances.
The novelty-routinization theory incorporates the more traditional distinction between verbal and nonverbal functions as a special case, but is more dynamic in nature, allows for evolutionary continuities, and provides a neurodevelopmental framework.
Books
- Elkhonon Goldberg. Contemporary Neuropsychology and the Legacy of Luria, Hillsdale, NJ: Lawrence Erlbaum, 1990. ISBN 978-0805803341
- Elkhonon Goldberg. The Executive Brain: Frontal Lobes and the Civilized Mind, NY: Oxford University Press, 2001; paperback 2002. ISBN 978-0195156300
- Elkhonon Goldberg. The Wisdom Paradox: How Your Mind Can Grow Stronger As Your Brain Grows Older, NY: Penguin, 2005; paperback 2006. UK edition: Free Press, Simon & Schuster, 2005. ISBN 1592401872
- Elkhonon Goldberg. The New Executive Brain: Frontal Lobes in a Complex World, NY: Oxford University Press, 2009. ISBN 978-0195329407
External links
- Brain Fitness, interview with Elkhonon Goldberg