DnaX
Encyclopedia
DnaX is the gene
that codes for the τ and γ subunits of the DNA clamp loader of prokaryotes. The eukaryotic equivalent to the DNA clamp loader is Replication Factor C
, which is encoded by RFC1
, RFC2
, RFC3
, RFC4
, and RFC5
.
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
that codes for the τ and γ subunits of the DNA clamp loader of prokaryotes. The eukaryotic equivalent to the DNA clamp loader is Replication Factor C
Replication factor C
The replication factor C, or RFC, is a five-subunit protein complex that is required for DNA replication.The subunits of this heteropentamer are named Rfc1, Rfc2, Rfc3, Rfc4, and Rfc5 . RFC is used in eukaryotic replication as a clamp loader, similar to the γ Complex in E. coli. Its role as clamp...
, which is encoded by RFC1
RFC1
Replication factor C subunit 1 is a protein that in humans is encoded by the RFC1 gene.-Interactions:RFC1 has been shown to interact with BRD4, HDAC1, RFC3, RELA and PCNA.-Further reading:...
, RFC2
RFC2
Replication factor C subunit 2 is a protein that in humans is encoded by the RFC2 gene.-Interactions:RFC2 has been shown to interact with BRD4, CHTF18, PCNA, RFC4 and RFC5.-Further reading:...
, RFC3
RFC3
Replication factor C subunit 3 is a protein that in humans is encoded by the RFC3 gene.-Interactions:RFC3 has been shown to interact with BRD4, CHTF18, RFC1, PCNA and RFC4.-Further reading:...
, RFC4
RFC4
Replication factor C subunit 4 is a protein that in humans is encoded by the RFC4 gene.-Interactions:RFC4 has been shown to interact with BRD4, RFC2, RFC3, CHTF18, PCNA and RFC5.-Further reading:...
, and RFC5
RFC5
Replication factor C subunit 5 is a protein that in humans is encoded by the RFC5 gene.-Interactions:RFC5 has been shown to interact with BRD4, RFC2, PCNA, RFC4 and CHTF18.-Further reading:...
.