DYX1C1
Encyclopedia
Dyslexia susceptibility 1 candidate gene 1 protein is a protein
that in humans is encoded by the DYX1C1 gene
. This protein contains 420-amino acids with 3 tetratricopeptide
repeat (TPR) domains, thought to mediate protein–protein interactions.
(dyslexia
).
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the DYX1C1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. This protein contains 420-amino acids with 3 tetratricopeptide
Tetratricopeptide
The tetratricopeptide repeat is a structural motif. It consists in a degenerate 34 amino acid sequence motif identified in a wide variety of proteins. It is found in tandem arrays of 3–16 motifs, which form scaffolds to mediate protein–protein interactions and often the assembly of multiprotein...
repeat (TPR) domains, thought to mediate protein–protein interactions.
Clinical significance
A mutation in the DYX1C1 gene has been associated with deficits in reading abilityReading disability
A reading disability is a condition in which a sufferer displays difficulty reading resulting primarily from neurological factors. Developmental Dyslexia, Alexia , and Hyperlexia.-Definition:...
(dyslexia
Dyslexia
Dyslexia is a very broad term defining a learning disability that impairs a person's fluency or comprehension accuracy in being able to read, and which can manifest itself as a difficulty with phonological awareness, phonological decoding, orthographic coding, auditory short-term memory, or rapid...
).