Cyanopsia
Encyclopedia
Cyanopsia is a medical
Ophthalmology
Ophthalmology is the branch of medicine that deals with the anatomy, physiology and diseases of the eye. An ophthalmologist is a specialist in medical and surgical eye problems...

 term for seeing
Visual perception
Visual perception is the ability to interpret information and surroundings from the effects of visible light reaching the eye. The resulting perception is also known as eyesight, sight, or vision...

 everything tinted with blue
Blue
Blue is a colour, the perception of which is evoked by light having a spectrum dominated by energy with a wavelength of roughly 440–490 nm. It is considered one of the additive primary colours. On the HSV Colour Wheel, the complement of blue is yellow; that is, a colour corresponding to an equal...

. It is also referred to as blue vision. Cyanopsia often occurs for a few days, weeks, or months after removal of a cataract
Cataract
A cataract is a clouding that develops in the crystalline lens of the eye or in its envelope, varying in degree from slight to complete opacity and obstructing the passage of light...

 from the eye
Human eye
The human eye is an organ which reacts to light for several purposes. As a conscious sense organ, the eye allows vision. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth...

. Cyanopsia also sometimes occurs as a side effect
Adverse effect
In medicine, an adverse effect is a harmful and undesired effect resulting from a medication or other intervention such as surgery.An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect. If it results from an unsuitable or incorrect dosage or...

 of taking sildenafil
Sildenafil
Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension . It was originally developed by British scientists and then brought to market by the US-based pharmaceutical company Pfizer...

 (Viagra), Cialis, or Levitra (Viagra and vision, n.d.).

Cyanopsia is a medical symptom
Symptom
A symptom is a departure from normal function or feeling which is noticed by a patient, indicating the presence of disease or abnormality...

 and not a sign
Medical sign
A medical sign is an objective indication of some medical fact or characteristic that may be detected by a physician during a physical examination of a patient....

. It is a purely subjective state, and can be caused by a physical or functional abnormality of the eye, a physical or functional abnormality of the brain, or by nothing at all (i.e., it can be purely psychological). Cyanopsia, if unaccompanied by any other sign or symptom, is not an indication of any disease or disorder. Unless it causes an impairment or significant distress, it is not in and of itself diagnostically relevant.

Cyanopsia after cataract removal

The eye's lens
Lens (anatomy)
The crystalline lens is a transparent, biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina. The lens, by changing shape, functions to change the focal distance of the eye so that it can focus on objects at various distances, thus allowing a...

 is normally tinted yellow
Yellow
Yellow is the color evoked by light that stimulates both the L and M cone cells of the retina about equally, with no significant stimulation of the S cone cells. Light with a wavelength of 570–590 nm is yellow, as is light with a suitable mixture of red and green...

. This reduces the intensity of blue light
Light
Light or visible light is electromagnetic radiation that is visible to the human eye, and is responsible for the sense of sight. Visible light has wavelength in a range from about 380 nanometres to about 740 nm, with a frequency range of about 405 THz to 790 THz...

 reaching the retina
Retina
The vertebrate retina is a light-sensitive tissue lining the inner surface of the eye. The optics of the eye create an image of the visual world on the retina, which serves much the same function as the film in a camera. Light striking the retina initiates a cascade of chemical and electrical...

. When the lens is removed because of cataract
Cataract
A cataract is a clouding that develops in the crystalline lens of the eye or in its envelope, varying in degree from slight to complete opacity and obstructing the passage of light...

, it is usually replaced by an artificial intraocular lens
Intraocular lens
An intraocular lens is an implanted lens in the eye, usually replacing the existing crystalline lens because it has been clouded over by a cataract, or as a form of refractive surgery to change the eye's optical power. It usually consists of a small plastic lens with plastic side struts, called...

; these artificial lenses are clear, allowing more intense blue light than usual to fall on the retina, leading to the phenomenon.

Hayashi and Hayashi (2006) compared visual function in people given yellow-tinted intraocular lenses with that in people given non-tinted intraocular lenses. Those with the yellow-tinted lenses were less likely to report cyanopsia than those with the clear lenses. Hayashi and Hayashi found no differences in visual acuity
Visual acuity
Visual acuity is acuteness or clearness of vision, which is dependent on the sharpness of the retinal focus within the eye and the sensitivity of the interpretative faculty of the brain....

 or in contrast sensitivity between the two groups.They also found that no one reported cyanopsia three months after the cataract operation, suggesting that some form of neural adaptation
Neural adaptation
Neural adaptation or sensory adaptation is a change over time in the responsiveness of the sensory system to a constant stimulus. It is usually experienced as a change in the stimulus. For example, if one rests one's hand on a table, one immediately feels the table's surface on one's skin. Within a...

 or colour constancy had taken place.

Cyanopsia from sildenafil

The author of Viagra and vision (n.d.) attributes cyanopsia after taking sildenafil to diminished enzyme activity sensitising the retinal rod cells. Rod cells are most sensitive to light of wavelengths near 498 nm; such light appears blue-green. When light levels are low enough for both rods and cone cell
Cone cell
Cone cells, or cones, are photoreceptor cells in the retina of the eye that are responsible for color vision; they function best in relatively bright light, as opposed to rod cells that work better in dim light. If the retina is exposed to an intense visual stimulus, a negative afterimage will be...

s to be active (mesopic vision
Mesopic vision
Mesopic vision is a combination of photopic vision and scotopic vision in low but not quite dark lighting situations. Mesopic light levels range from luminances of approximately 0.001 to 3 cd m-2. Most night-time outdoor and traffic lighting scenarios are in the mesopic range.Humans see...

) the enhanced rod activity induces the bluish visual tint.

External links

  • http://www.psych.ucalgary.ca/pace/va-lab/Brian/acquired.htm for illustrations of various colour deficiencies including cyanopsia.
The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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