Corticovirus
Encyclopedia
The Corticoviridae is a family of phages with a double stranded DNA genome that infect bacteria. The name is derived from Latin cortex, corticis (meaning 'crust' or 'bark').
The family has a single genus - Corticovirus.
The type species is Alteromonas phage PM2 which is currently the only known species in this genus.
This family of viruses has been little studied and not much is known about it.
of a diameter of 60 nm and an internal lipid
membrane
located between outer and inner protein
shell. The shells are composed of three layers which surfaces reveals a pattern with distinctive features, including bush-like spikes protruding from the twelve vertices
.
The icosahedral capsid ( (T = 12 or 13) is 56 nanometers (nm) in diameter and is composed of 1200 P1 (spike) and 60 P2 (capsid) proteins. The pentameric receptor-binding spikes protrude from the 12 fivefold axes. The capsid encloses an internal lipid core containing the structural proteins P3 to P9.
of 9.5-12 kilobases
in length. The genome has a g
+ c
content of 43%. It encodes ~21 proteins.
Transcription is organised into three operons.
Replication of the genome is via a rolling-circle mechanism.
The family has a single genus - Corticovirus.
The type species is Alteromonas phage PM2 which is currently the only known species in this genus.
This family of viruses has been little studied and not much is known about it.
Virology
The virons consist of a round, icosahedral, non-enveloped capsidCapsid
A capsid is the protein shell of a virus. It consists of several oligomeric structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The capsid encloses the genetic...
of a diameter of 60 nm and an internal lipid
Lipid
Lipids constitute a broad group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins , monoglycerides, diglycerides, triglycerides, phospholipids, and others...
membrane
Cell membrane
The cell membrane or plasma membrane is a biological membrane that separates the interior of all cells from the outside environment. The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances in and out of cells. It basically protects the cell...
located between outer and inner protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
shell. The shells are composed of three layers which surfaces reveals a pattern with distinctive features, including bush-like spikes protruding from the twelve vertices
Vertex (geometry)
In geometry, a vertex is a special kind of point that describes the corners or intersections of geometric shapes.-Of an angle:...
.
The icosahedral capsid ( (T = 12 or 13) is 56 nanometers (nm) in diameter and is composed of 1200 P1 (spike) and 60 P2 (capsid) proteins. The pentameric receptor-binding spikes protrude from the 12 fivefold axes. The capsid encloses an internal lipid core containing the structural proteins P3 to P9.
Genome
The genome is not segmented, constitutes 13% of the virus's weight and contains a single molecule of circular, supercoiled, double-stranded DNADNA
Deoxyribonucleic acid is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms . The DNA segments that carry this genetic information are called genes, but other DNA sequences have structural purposes, or are involved in...
of 9.5-12 kilobases
Base pair
In molecular biology and genetics, the linking between two nitrogenous bases on opposite complementary DNA or certain types of RNA strands that are connected via hydrogen bonds is called a base pair...
in length. The genome has a g
Guanine
Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine . In DNA, guanine is paired with cytosine. With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with...
+ c
Cytosine
Cytosine is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine . It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached . The nucleoside of cytosine is cytidine...
content of 43%. It encodes ~21 proteins.
Transcription is organised into three operons.
Replication of the genome is via a rolling-circle mechanism.