Cavum septum pellucidum
Encyclopedia
Cavum septum pellucidum (CSP) describes a septum pellucidum
Septum pellucidum
The septum pellucidum , and not to be confused with the medial septum, is a thin, triangular, vertical membrane separating the anterior horns of the left and right lateral ventricles of the brain...

 that has a separation between its two leaflets (septal laminae). This cavity contains cerebrospinal fluid
Cerebrospinal fluid
Cerebrospinal fluid , Liquor cerebrospinalis, is a clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord...

 (CSF) that filters from the ventricles through the septal laminae
.

CSP is bounded anteriorly by the genu of the corpus callosum
Corpus callosum
The corpus callosum , also known as the colossal commissure, is a wide, flat bundle of neural fibers beneath the cortex in the eutherian brain at the longitudinal fissure. It connects the left and right cerebral hemispheres and facilitates interhemispheric communication...

; superiorly by the body of the corpus callosum; posteriorly by the anterior limb and pillars of the fornix; inferiorly by the anterior commissure
Anterior commissure
The anterior commissure is a bundle of nerve fibers , connecting the two cerebral hemispheres across the midline, and placed in front of the columns of the fornix...

and the rostrum of the corpus callosum; and laterally by the leaflets of the septum pellucidum
.

The most common type of CSP is noncommunicating, that is, it does not connect to the brain's ventricular system. Because of this lack of communication, the erstwhile term for CSP, the "fifth ventricle," is not anatomically correct and its use has fallen out of favor in recent years.

CSP is present in 100% of fetuses, but over 85% of them fuse by 3–6 months after birth
. It has been loosely associated with schizophrenia, post-traumatic stress disorder, and chronic brain trauma
.

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