Camillo Bozzolo
Encyclopedia
Camillo Bozzolo was an Italian physician who was a native of Milan
. In 1868 he received his medical doctorate from the University of Pavia
, and afterwards continued his studies in Austria and Germany at the laboratories of Johann von Oppolzer
(1808–1871), Ludwig Traube
(1818–1876) and Rudolf Virchow
(1821–1902). Later he was an assistant pathologist to Giulio Bizzozero
(1846–1901) in Turin
, and in 1883 a professor and director of the medical clinic in Turin.
His earlier studies dealt with metastasis
of cancer
involving the bloodstream
and lymph glands. With Edoardo Perroncito (1847–1936) and Luigi Pagliani (1847–1931), he discovered that hookworm
(Ancylostoma duodenale) was the cause of anemia
affecting workmen building the St. Gotthard
Railway. In addition, he is credited for introducing thymol
as treatment for hookworm.
Milan
Milan is the second-largest city in Italy and the capital city of the region of Lombardy and of the province of Milan. The city proper has a population of about 1.3 million, while its urban area, roughly coinciding with its administrative province and the bordering Province of Monza and Brianza ,...
. In 1868 he received his medical doctorate from the University of Pavia
University of Pavia
The University of Pavia is a university located in Pavia, Lombardy, Italy. It was founded in 1361 and is organized in 9 Faculties.-History:...
, and afterwards continued his studies in Austria and Germany at the laboratories of Johann von Oppolzer
Johann Ritter von Oppolzer
Johann Ritter von Oppolzer was an Austrian physician born in Nové Hrady, Bohemia. He was the father of the astronomer Theodor von Oppolzer ....
(1808–1871), Ludwig Traube
Ludwig Traube (physician)
Ludwig Traube was a German physician and co-founder of the experimental pathology in Germany.-Biography:...
(1818–1876) and Rudolf Virchow
Rudolf Virchow
Rudolph Carl Virchow was a German doctor, anthropologist, pathologist, prehistorian, biologist and politician, known for his advancement of public health...
(1821–1902). Later he was an assistant pathologist to Giulio Bizzozero
Giulio Bizzozero
Giulio Bizzozero was an Italian doctor and medical researcher. He is known as the original discoverer of Helicobacter pylori, the bacteria which is responsible for peptic ulcer disease...
(1846–1901) in Turin
Turin
Turin is a city and major business and cultural centre in northern Italy, capital of the Piedmont region, located mainly on the left bank of the Po River and surrounded by the Alpine arch. The population of the city proper is 909,193 while the population of the urban area is estimated by Eurostat...
, and in 1883 a professor and director of the medical clinic in Turin.
His earlier studies dealt with metastasis
Metastasis
Metastasis, or metastatic disease , is the spread of a disease from one organ or part to another non-adjacent organ or part. It was previously thought that only malignant tumor cells and infections have the capacity to metastasize; however, this is being reconsidered due to new research...
of cancer
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...
involving the bloodstream
Circulatory system
The circulatory system is an organ system that passes nutrients , gases, hormones, blood cells, etc...
and lymph glands. With Edoardo Perroncito (1847–1936) and Luigi Pagliani (1847–1931), he discovered that hookworm
Hookworm
The hookworm is a parasitic nematode that lives in the small intestine of its host, which may be a mammal such as a dog, cat, or human. Two species of hookworms commonly infect humans, Ancylostoma duodenale and Necator americanus. A. duodenale predominates in the Middle East, North Africa, India...
(Ancylostoma duodenale) was the cause of anemia
Anemia
Anemia is a decrease in number of red blood cells or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin...
affecting workmen building the St. Gotthard
Gotthard Rail Tunnel
The Gotthard Rail Tunnel, is a 15-kilometre long railway tunnel and forms the summit of the Gotthard Railway in Switzerland. It connects Göschenen with Airolo and was the first tunnel through the Gotthard massif...
Railway. In addition, he is credited for introducing thymol
Thymol
Thymol is a natural monoterpene phenol derivative of cymene, C10H14O, isomeric with carvacrol, found in oil of thyme, and extracted from Thymus vulgaris and various other kinds of plants as a white crystalline substance of a pleasant aromatic odor and strong antiseptic properties...
as treatment for hookworm.
Associated eponyms
- Kahler-Bozzolo disease: (also Kahler's disease) a fatal condition with occurrence of multiple myelomaMultiple myelomaMultiple myeloma , also known as plasma cell myeloma or Kahler's disease , is a cancer of plasma cells, a type of white blood cell normally responsible for the production of antibodies...
in the bone marrowBone marrowBone marrow is the flexible tissue found in the interior of bones. In humans, bone marrow in large bones produces new blood cells. On average, bone marrow constitutes 4% of the total body mass of humans; in adults weighing 65 kg , bone marrow accounts for approximately 2.6 kg...
. Named with Otto KahlerOtto KahlerOtto Kahler was an Austrian physician. Born and trained in Prague, he is best known for describing multiple myeloma, a hematological malignancy, which is called "Kahler's disease" in his honor in several countries...
(1849–1893). - Bozzolo's sign: Pulsating vessels in the nasal mucous membrane, seen sometimes in aneurysmAneurysmAn aneurysm or aneurism is a localized, blood-filled balloon-like bulge in the wall of a blood vessel. Aneurysms can commonly occur in arteries at the base of the brain and an aortic aneurysm occurs in the main artery carrying blood from the left ventricle of the heart...
of the thoracic aortaThoracic aortaThe thoracic aorta is contained in the posterior mediastinal cavity.It begins at the lower border of the fourth thoracic vertebra where it is continuous with the aortic arch, and ends in front of the lower border of the twelfth thoracic vertebra, at the aortic hiatus in the diaphragm where it...
.