Calcifying odontogenic cyst
Encyclopedia
The calcifying odotogenic cyst, also known as the Gorlin cyst, is a cyst
most likely to affect the anterior areas of the jaw
s. It is most common in people in their second to third decades but can be seen at almost any age. On radiographs, the calcifying odontogenic cyst appears as a unilocular radiolucency (dark area). In one-third of cases, an impacted tooth is involved. Microscopically
, there are many cells that are described as "ghost cells", enlarged eosinophilic epithelial cells without nuclei.
Diameter is 2 to 4 cm
Histopathology
In general, the epithelium seen is of stratified squamous type and is 2–3 cells thick. Additionally, focal areas of stellate reticulum like cells are seen and near the basement membrane ameloblast-like cells may be seen.
Each type of COC shows special features:
Of three types:
1)Type 1A
Ghost cells plus dentinoid are seen
2)Type 1B
Formation of calcified tissues in the lumen of the cyst wall --> Dystrophic Calcification.
Proliferation of tissue similar to an Ameloblastic Fibroma.
3)Type 1C
Ameloblast like proliferation in the connective tissue and lumen of the cyst may be seen.
Radiographic features
Unilocular radiolucency may be seen. irregular calcifications may be seen in some cases.
Cyst
A cyst is a closed sac, having a distinct membrane and division on the nearby tissue. It may contain air, fluids, or semi-solid material. A collection of pus is called an abscess, not a cyst. Once formed, a cyst could go away on its own or may have to be removed through surgery.- Locations :* Acne...
most likely to affect the anterior areas of the jaw
Jaw
The jaw is any opposable articulated structure at the entrance of the mouth, typically used for grasping and manipulating food. The term jaws is also broadly applied to the whole of the structures constituting the vault of the mouth and serving to open and close it and is part of the body plan of...
s. It is most common in people in their second to third decades but can be seen at almost any age. On radiographs, the calcifying odontogenic cyst appears as a unilocular radiolucency (dark area). In one-third of cases, an impacted tooth is involved. Microscopically
Microscope
A microscope is an instrument used to see objects that are too small for the naked eye. The science of investigating small objects using such an instrument is called microscopy...
, there are many cells that are described as "ghost cells", enlarged eosinophilic epithelial cells without nuclei.
Clinical features
It can occur at any age,mostly between 2nd and 3rd decade of life.Diameter is 2 to 4 cm
Histopathology
In general, the epithelium seen is of stratified squamous type and is 2–3 cells thick. Additionally, focal areas of stellate reticulum like cells are seen and near the basement membrane ameloblast-like cells may be seen.
Each type of COC shows special features:
Of three types:
1)Type 1A
Ghost cells plus dentinoid are seen
2)Type 1B
Formation of calcified tissues in the lumen of the cyst wall --> Dystrophic Calcification.
Proliferation of tissue similar to an Ameloblastic Fibroma.
3)Type 1C
Ameloblast like proliferation in the connective tissue and lumen of the cyst may be seen.
Radiographic features
Unilocular radiolucency may be seen. irregular calcifications may be seen in some cases.