CAD (gene)
Encyclopedia
CAD is a gene which encodes several enzymes involved in pyrimidine biosynthesis. De-novo synthesis starts with cytosol
ic carbamoylphosphate synthetase II which uses glutamine
, carbon dioxide
and 2 ATP
. This enzyme is inhibited by UTP.
Cytosol
The cytosol or intracellular fluid is the liquid found inside cells, that is separated into compartments by membranes. For example, the mitochondrial matrix separates the mitochondrion into compartments....
ic carbamoylphosphate synthetase II which uses glutamine
Glutamine
Glutamine is one of the 20 amino acids encoded by the standard genetic code. It is not recognized as an essential amino acid but may become conditionally essential in certain situations, including intensive athletic training or certain gastrointestinal disorders...
, carbon dioxide
Carbon dioxide
Carbon dioxide is a naturally occurring chemical compound composed of two oxygen atoms covalently bonded to a single carbon atom...
and 2 ATP
Adenosine triphosphate
Adenosine-5'-triphosphate is a multifunctional nucleoside triphosphate used in cells as a coenzyme. It is often called the "molecular unit of currency" of intracellular energy transfer. ATP transports chemical energy within cells for metabolism...
. This enzyme is inhibited by UTP.