Braun's lipoprotein
Encyclopedia
Braun's lipoprotein found in gram-negative
cell walls, is one of the most abundant membrane protein
s; its molecular weight is about 7.2 kDa. It is bound at its C-terminal end (a lysine
) by a covalent bond
to the peptidoglycan
layer (specifically to diaminopimelic acid
molecules) and is embedded in the outer membrane by its hydrophobic head (a cysteine
with lipids attached). BLP tightly links the two layers and provides structural integrity to the outer membrane.
Gram-negative
Gram-negative bacteria are bacteria that do not retain crystal violet dye in the Gram staining protocol. In a Gram stain test, a counterstain is added after the crystal violet, coloring all Gram-negative bacteria with a red or pink color...
cell walls, is one of the most abundant membrane protein
Membrane protein
A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. More than half of all proteins interact with membranes.-Function:...
s; its molecular weight is about 7.2 kDa. It is bound at its C-terminal end (a lysine
Lysine
Lysine is an α-amino acid with the chemical formula HO2CCH4NH2. It is an essential amino acid, which means that the human body cannot synthesize it. Its codons are AAA and AAG....
) by a covalent bond
Covalent bond
A covalent bond is a form of chemical bonding that is characterized by the sharing of pairs of electrons between atoms. The stable balance of attractive and repulsive forces between atoms when they share electrons is known as covalent bonding....
to the peptidoglycan
Peptidoglycan
Peptidoglycan, also known as murein, is a polymer consisting of sugars and amino acids that forms a mesh-like layer outside the plasma membrane of bacteria , forming the cell wall. The sugar component consists of alternating residues of β- linked N-acetylglucosamine and N-acetylmuramic acid...
layer (specifically to diaminopimelic acid
Diaminopimelic acid
Diaminopimelic acid is an amino acid, representing an epsilon-carboxy derivative of lysine.DAP is a characteristic of certain cell walls of some bacteria. When provided, they exhibit normal growth. When in deficiency, they still grow but with the inability to make new cell wall proteoglycan.This...
molecules) and is embedded in the outer membrane by its hydrophobic head (a cysteine
Cysteine
Cysteine is an α-amino acid with the chemical formula HO2CCHCH2SH. It is a non-essential amino acid, which means that it is biosynthesized in humans. Its codons are UGU and UGC. The side chain on cysteine is thiol, which is polar and thus cysteine is usually classified as a hydrophilic amino acid...
with lipids attached). BLP tightly links the two layers and provides structural integrity to the outer membrane.