Aquamid
Encyclopedia
Aquamid is a non-absorbable soft volume filler for aesthetic and reconstructive purposes. Aquamid is the trade name for a specific formulation of 97.5% water for injection and 2.5% cross-linked polyacrylamide
. It is injected subcutaneously
to correct wrinkle
s and folds or to add volume. Common aesthetic indications are nasolabial folds, lip augmentation
, cheek contouring, nose enhancement. Aquamid is also used to correct signs of facial lipoatrophy or fat wasting in HIV+ patients.
Aquamid has been evaluated in several clinical trial
s involving more than 5,000 patients including a comparative trial in the United States. Data from this trial has been used to support a PMA application to the FDA
. Aquamid is not yet approved for sale in the United States.
Aquamid is developed, produced and commercialized by Contura International. It was approved in Europe in 2001 for facial augmentation and minor body contouring and is available in several countries in Europe, Asia, the Middle East and Latin America.
Polyacrylamide
Polyacrylamide is a polymer formed from acrylamide subunits. It can be synthesized as a simple linear-chain structure or cross-linked, typically using N,N-methylenebisacrylamide. Polyacrylamide is not toxic...
. It is injected subcutaneously
Subcutaneous tissue
The hypodermis, also called the hypoderm, subcutaneous tissue, or superficial fascia is the lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages...
to correct wrinkle
Wrinkle
A wrinkle is a fold, ridge or crease in the skin. Skin wrinkles typically appear as a result of aging processes such as glycation or, temporarily, as the result of prolonged immersion in water. Wrinkling in the skin is caused by habitual facial expressions, aging, sun damage, smoking, poor...
s and folds or to add volume. Common aesthetic indications are nasolabial folds, lip augmentation
Lip enhancement
Lip enhancement is a type of cosmetic surgery or non-surgical procedure that aims to improve the appearance of the lips by increasing their fullness through enlargement.-History:...
, cheek contouring, nose enhancement. Aquamid is also used to correct signs of facial lipoatrophy or fat wasting in HIV+ patients.
Aquamid has been evaluated in several clinical trial
Clinical trial
Clinical trials are a set of procedures in medical research and drug development that are conducted to allow safety and efficacy data to be collected for health interventions...
s involving more than 5,000 patients including a comparative trial in the United States. Data from this trial has been used to support a PMA application to the FDA
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
. Aquamid is not yet approved for sale in the United States.
Aquamid is developed, produced and commercialized by Contura International. It was approved in Europe in 2001 for facial augmentation and minor body contouring and is available in several countries in Europe, Asia, the Middle East and Latin America.