Angioblast
Encyclopedia
Blood vessels first make their appearance in several scattered vascular areas that are developed simultaneously between the endoderm
Endoderm
Endoderm is one of the three primary germ cell layers in the very early embryo. The other two layers are the ectoderm and mesoderm , with the endoderm as the intermost layer...

 and the mesoderm
Mesoderm
In all bilaterian animals, the mesoderm is one of the three primary germ cell layers in the very early embryo. The other two layers are the ectoderm and endoderm , with the mesoderm as the middle layer between them.The mesoderm forms mesenchyme , mesothelium, non-epithelial blood corpuscles and...

 of the yolk-sac, i. e., outside the body of the embryo
Embryo
An embryo is a multicellular diploid eukaryote in its earliest stage of development, from the time of first cell division until birth, hatching, or germination...

. Here a new type of cell, the angioblast or vasoformative cell, is differentiated from the mesoderm.

These cells as they divide form small, dense syncytial masses, which soon join with similar masses by means of fine processes to form plexuses.

Angioblasts are one of the two products formed from hemangioblasts (the other being pluripotential hemopoietic stem cell
Pluripotential hemopoietic stem cell
Hematopoietic stem cells , also spelled Hæmatopoietic stem cells, are multipotent stem cells that give rise to all the blood cell types from the myeloid , and lymphoid lineages...

s).

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