ATF3
Encyclopedia
Cyclic AMP-dependent transcription factor ATF-3 is a protein
that, in humans, is encoded by the ATF3 gene
.
with JunD
, C-jun
, Mothers against decapentaplegic homolog 3
, DNA damage-inducible transcript 3
and P53
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that, in humans, is encoded by the ATF3 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
ATF3 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with JunD
JunD
Transcription factor jun-D is a protein that in humans is encoded by the JUND gene.-Interactions:JunD has been shown to interact with ATF3, MEN1, DNA damage-inducible transcript 3 and BRCA1....
, C-jun
C-jun
c-Jun is the name of a gene and protein that, in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the...
, Mothers against decapentaplegic homolog 3
Mothers against decapentaplegic homolog 3
Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins.The human SMAD3 gene is located on chromosome 15...
, DNA damage-inducible transcript 3
DNA damage-inducible transcript 3
DNA damage-inducible transcript 3 is a protein that in humans is encoded by the DDIT3 gene.-Interactions:DNA damage-inducible transcript 3 has been shown to interact with Casein kinase 2, alpha 1, JunD, RPS3A, ATF3, CEBPB, C-jun and C-Fos....
and P53
P53
p53 , is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer...
.