N07AA Anticholinesterases

N07AA01 Neostigmine

Neostigmine

Neostigmine is a parasympathomimetic that acts as a reversible acetylcholinesterase inhibitor.- Synthesis :Neostigmine was first synthesized by Aeschlimann and Reinert in 1931....

N07AA02 Pyridostigmine

Pyridostigmine

Pyridostigmine is a parasympathomimetic and a reversible cholinesterase inhibitor. Since it is a quaternary amine, it is poorly absorbed in the gut and does not cross the blood-brain barrier, except possibly in stressful conditions.-Mode of action:...

N07AA03 Distigmine

Distigmine

Distigmine is a parasympathomimetic. Distigmine is similar to pyridostigmine and neostigmine but has a longer duration of action. It is available as tablets on prescription only...

N07AA30 Ambenonium

N07AA51 Neostigmine, combinations

N07AX Other parasympathomimetics

N07AX01 Pilocarpine

Pilocarpine

Pilocarpine is a parasympathomimetic alkaloid obtained from the leaves of tropical American shrubs from the genus Pilocarpus. It is a non-selective muscarinic receptor agonist in the parasympathetic nervous system, which acts therapeutically at the muscarinic acetylcholine receptor M3 due to its...

N07AX02 Choline alfoscerate

N07AX03 Cevimeline

N07BA Drugs used in nicotine

Nicotine

Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6–3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves...

 dependence

N07BA01 Nicotine

Nicotine

Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6–3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves...

N07BA03 Varenicline

N07BB Drugs used in alcohol dependence

Alcohol dependence

Alcohol dependence, as described in the DSM-IV, is a psychiatric diagnosis describing an entity in which an individual uses alcohol despite significant areas of dysfunction, evidence of physical dependence, and/or related hardship.-Definition and diagnosis:According to the DSM-IV criteria for...

N07BB01 Disulfiram

Disulfiram

Disulfiram is a drug discovered in the 1920s and used to support the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Trade names for disulfiram in different countries are Antabuse and Antabus manufactured by Odyssey Pharmaceuticals...

N07BB02 Calcium carbimide

N07BB03 Acamprosate

Acamprosate

Acamprosate, also known as N-acetyl homotaurine and by the brand name Campral, is a drug used for treating alcohol dependence.Acamprosate is thought to stabilize the chemical balance in the brain that would otherwise be disrupted by alcoholism, possibly by blocking glutamatergic...

N07BB04 Naltrexone

Naltrexone

Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. It is marketed in generic form as its hydrochloride salt, naltrexone hydrochloride, and marketed under the trade names Revia and Depade...

N07BC Drugs used in opioid dependence

N07BC01 Buprenorphine

Buprenorphine

Buprenorphine is a semi-synthetic opioid that is used...

N07BC02 Methadone

Methadone

Methadone is a synthetic opioid, used medically as an analgesic and a maintenance anti-addictive for use in patients with opioid dependency. It was developed in Germany in 1937...

N07BC03 Levacetylmethadol

Levacetylmethadol

Levacetylmethadol , levomethadyl acetate , Orlaam or levo-α-acetylmethadol is a synthetic opioid similar in structure to methadone. It has a long duration of action due to its active metabolites. It was approved in 1993 by the U.S. Food and Drug Administration for use in the treatment of opioid...

N07BC04 Lofexidine

Lofexidine

Lofexidine is an alpha2-adrenergic receptor agonist, historically used as a short-acting anti-hypertensive, but more commonly used to alleviate physical symptoms of heroin and opiate withdrawal.-Indication:...

N07BC51 Buprenorphine, combinations

N07CA Antivertigo preparations

N07CA01 Betahistine

Betahistine

Betahistine hydrochloride is an antivertigo drug. It was first registered in Europe in 1970 for the treatment of Ménière's disease...

N07CA02 Cinnarizine

Cinnarizine

Cinnarizine is an antihistamine which is mainly used for the control of nausea and vomiting due to motion sickness. Cinnarizine was first synthesized by Janssen Pharmaceutica in 1955...

N07CA03 Flunarizine

Flunarizine

Flunarizine is a drug classified as a calcium channel blocker. Flunarizine is a non-selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and...

N07CA04 Acetylleucine

Acetylleucine

Acetylleucine is a drug used in the treatment of vertigo....

N07CA52 Cinnarizine, combinations

N07XX Other nervous system drugs

N07XX01 Tirilazad

Tirilazad

Tirilazad is a drug proposed for use in the treatment of stroke, though results so far have been mixed....

N07XX02 Riluzole

Riluzole

Riluzole is a drug used to treat amyotrophic lateral sclerosis. It delays the onset of ventilator-dependence or tracheostomy in selected patients and may increase survival by approximately 3–5 months....

N07XX03 Xaliproden

Xaliproden

Xaliproden is a drug which acts as a 5HT1A agonist. It has neurotrophic and neuroprotective effects in vitro, and has been proposed for use in the treatment of several neurodegenerative conditions including amyotrophic lateral sclerosis and Alzheimer's disease.Development of xaliproden for these...

N07XX04 Sodium oxybate

N07XX05 Amifampridine

N07XX06 Tetrabenazine

Tetrabenazine

Tetrabenazine is a drug for the symptomatic treatment of hyperkinetic movement disorder and is marketed under the trade names Nitoman in Canada and Xenazine in New Zealand and some parts of Europe, and is also available in the USA as an orphan drug. On August 15, 2008 the U.S...

N07XX07 Fampridine