ADIPOR2
Encyclopedia
Adiponectin receptor 2 also known as ADIPOR2 is a protein
which in humans is encoded by the ADIPOR2 gene
.
and ADIPOR2 (this protein), serve as receptors for globular and full-length adiponectin
and mediate increased AMPK
and PPAR-α
ligand activities, as well as fatty acid
oxidation and glucose uptake by adiponectin.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
which in humans is encoded by the ADIPOR2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
The adiponectin receptors, ADIPOR1ADIPOR1
Adiponectin receptor 1, also known as ADIPOR1, is a protein which in humans is encoded by the ADIPOR1 gene.- Function :The adiponectin receptors, ADIPOR1 and ADIPOR2 , serve as receptors for globular and full-length adiponectin and mediate increased AMPK and PPAR-α ligand activities, as well as...
and ADIPOR2 (this protein), serve as receptors for globular and full-length adiponectin
Adiponectin
Adiponectin is a protein which in humans is encoded by the ADIPOQ gene.- Structure :...
and mediate increased AMPK
AMP-activated protein kinase
5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme that plays a role in cellular energy homeostasis. It consists of three proteins that together make a functional enzyme, conserved from yeast to humans. It is expressed in a number of...
and PPAR-α
Peroxisome proliferator-activated receptor alpha
Peroxisome proliferator-activated receptor alpha , also known as NR1C1 , is a nuclear receptor protein that in humans is encoded by the PPARA gene.- Function :...
ligand activities, as well as fatty acid
Fatty acid
In chemistry, especially biochemistry, a fatty acid is a carboxylic acid with a long unbranched aliphatic tail , which is either saturated or unsaturated. Most naturally occurring fatty acids have a chain of an even number of carbon atoms, from 4 to 28. Fatty acids are usually derived from...
oxidation and glucose uptake by adiponectin.