1796    Edward Jenner administers the first smallpox vaccination.

1977    The last natural case of smallpox is discovered in Merca district, Somalia. The WHO and the CDC consider this date the anniversary of the eradication of smallpox, the most spectacular success of vaccination.

1993    450 prisoners rioted at the Southern Ohio Correctional Facility in Lucasville, Ohio, and continued to do so for ten days, citing grievances related to prison conditions, as well as the forced vaccination of Nation of Islam prisoners (for tuberculosis) against their religious beliefs.