1821 The Republic of Gran Colombia (a federation covering much of present day Venezuela, Colombia, Panama, and Ecuador) is established, with Simón Bolívar as the founding President and Francisco de Paula Santander as vice president.
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1832 President Andrew Jackson writes to Vice President Martin Van Buren expressing his opposition to South Carolina's defiance of federal authority in the Nullification Crisis.
1999 Gunmen assassinate Paraguay's Vice President Luis María Argaña.