Noun

1. A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be.

Related terms

• Classifications of holoprosencephaly
  • alobar
  • semilobar
  • lobar
• Associated facial deformities
  • premaxillary agenesis
  • cyclopia
  • ethmocephaly
  • cebocephaly