Yuremamine
Encyclopedia
Yuremamine is a phytoindole alkaloid
Alkaloid
Alkaloids are a group of naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids...

 which was isolated and identified from the bark of Mimosa tenuiflora in 2005. It may explain the oral psychoactivity of traditional preparations from Mimosa tenuiflora, which also contains DMT (dimethyltryptamine
Dimethyltryptamine
N,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...

).

As a pure compound, yuremamine is a purple amorphous solid. It represents an entirely new family of indole
Indole
Indole is an aromatic heterocyclic organic compound. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. Indole is a popular component of fragrances and the precursor to many pharmaceuticals. Compounds that contain an...

 derivatives. It is interesting to note that this compound contains N,N-dimethyltryptamine within its molecular structure. Perhaps yuremamine acts as an MAOI, being metabolically protected itself through intra-molecular hydrogen bonding of its tertiary amine, or perhaps yuremamine acts as a prodrug and releases DMT closer to its site of action.

There has been speculation that yuremamine is identical with a crude substance described as a "dark red jungle spice", which has been solvent extracted from Mimosa tenuiflora, without the benefit of chromatographic separation. However, there is no analytical evidence to suggest that yuremamine has been isolated by home extractors, and it is likely that the substance will decompose at the typical acidic or basic conditions used in such extractions.
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