VDAC2
Encyclopedia
Voltage-dependent anion-selective channel protein 2 is a protein
that in humans is encoded by the VDAC2 gene
. The protein
encoded by this gene is a voltage-dependent anion channel
.
VDAC2 is involved in the regulation of mitochondrial
apoptosis
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the VDAC2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. The protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
encoded by this gene is a voltage-dependent anion channel
Voltage-dependent anion channel
Voltage-dependent anion channels are a class of porin ion channel located on the outer mitochondrial membrane.This major protein of the outer mitochondrial membrane of eukaryotes. It forms a voltage-dependent anion-selective channel that behaves as a general diffusion pore for small hydrophilic...
.
VDAC2 is involved in the regulation of mitochondrial
Mitochondrion
In cell biology, a mitochondrion is a membrane-enclosed organelle found in most eukaryotic cells. These organelles range from 0.5 to 1.0 micrometers in diameter...
apoptosis
Apoptosis
Apoptosis is the process of programmed cell death that may occur in multicellular organisms. Biochemical events lead to characteristic cell changes and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation...
.