USS Truxtun has been the name of various United States Navy ships, and may refer to:
, a brig launched in 1842 and destroyed after running aground off Mexico in 1846
, a destroyer in service from 1902 to 1919
, a destroyer commissioned in 1921 that ran aground and sank in 1942
, laid down as a destroyer escort (DE-282) in 1943, completed as a high-speed transport (APD-98) in 1945, and in commission as such from 1945 to 1946.
, originally guided missile destroyer leader DLGN-35, a guided missile cruiser in commission from 1967 to 1995
, an Arleigh Burke-class destroyer

Arleigh Burke class destroyer

The Arleigh Burke class of guided missile destroyers is the United States Navy's first class of destroyer built around the Aegis combat system and the SPY-1D multi-function phased array radar. The class is named for Admiral Arleigh "31-Knot" Burke, the most famous American destroyer officer of...

, commissioned in 2009.