UQCRC2
Encyclopedia
Cytochrome b-c1 complex subunit 2, mitochondrial is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the UQCRC2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

.

Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial cytochrome b
Cytochrome b
Cytochrome b/b6 is the main subunit of transmembrane cytochrome bc1 and b6f complexes. In addition, it commonly refers to a region of mtDNA used for population genetics and phylogenetics.- Function :...

) and ten nuclear genes: UQCRC1
UQCRC1
Cytochrome b-c1 complex subunit 1, mitochondrial is a protein that in humans is encoded by the UQCRC1 gene.Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase , which consists of the products of one mitochondrially encoded gene, MTCYTB and ten nuclear...

, UQCRC2, Cytochrome c1
Cytochrome C1
Cytochrome C1 is formed in the cytosol and targeted to the mitochondrial intermembrane space. It is one of the constituents of complex III, which forms the third proton pump in the mitochondrial electron transport chain....

, UQCRFS1
UQCRFS1
Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1, also known as UQCRFS1, is a protein which in humans is encoded by the UQCRFS1 gene....

 (Rieske protein
Rieske protein
Rieske proteins are iron-sulfur protein components of cytochrome bc1 complexes and cytochrome b6f complexes which were first discovered and isolated by John S. Rieske and co-workers in 1964. It is a unique [2Fe-2S] cluster in that one of the two Fe atoms is coordinated by two histidine residues...

), UQCRB
UQCRB
Ubiquinol-cytochrome c reductase binding protein, also known as UQCRB, is a protein which in humans is encoded by the UQCRB gene.- Function :...

, "11kDa protein", UQCRH
UQCRH
Cytochrome b-c1 complex subunit 6, mitochondrial is a protein that in humans is encoded by the UQCRH gene.Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase Cytochrome b-c1 complex subunit 6, mitochondrial is a protein that in humans is encoded by the...

(cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and "Rieske-associated protein".

Further reading

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