UPF1
Encyclopedia
Regulator of nonsense transcripts 1 is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the UPF1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

.

Interactions

UPF1 has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with UPF2
UPF2
Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene.-Interactions:UPF2 has been shown to interact with UPF1, UPF3A and UPF3B.-Further reading:...

, SMG1
SMG1 (gene)
Serine/threonine-protein kinase SMG1 is an enzyme that in humans is encoded by the SMG1 gene. SMG1 belongs to the phosphatidylinositol 3-kinase-related kinase protein family.-Interactions:SMG1 has been shown to interact with PRKCI and UPF1....

, DCP2
DCP2
mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene.-Interactions:DCP2 has been shown to interact with DCP1A and UPF1.-Further reading:...

, DCP1A
DCP1A
mRNA-decapping enzyme 1A is a protein that in humans is encoded by the DCP1A gene.-Interactions:DCP1A has been shown to interact with DCP2 and UPF1.-Further reading:...

, UPF3A
UPF3A
Regulator of nonsense transcripts 3A is a protein that in humans is encoded by the UPF3A gene.-Interactions:UPF3A has been shown to interact with RBM8A, UPF2 and UPF1.-Further reading:...

 and UPF3B
UPF3B
Regulator of nonsense transcripts 3B is a protein that in humans is encoded by the UPF3B gene.-Interactions:UPF3B has been shown to interact with UPF2 and UPF1.-Further reading:...

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Further reading

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