U7 small nuclear RNA
Encyclopedia
The U7 small nuclear RNA (U7 snRNP) is an RNA
molecule involved in the splicing
of metazoan histone
pre-mRNAs, which are spliced by a different mechanism than nuclear
pre-mRNAs and self-splicing intron
s. The 5' end of U7 RNA is thought to base-pair to a conserved spacer element downstream of the cleavage site in histone pre-mRNA.
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....
molecule involved in the splicing
RNA splicing
In molecular biology and genetics, splicing is a modification of an RNA after transcription, in which introns are removed and exons are joined. This is needed for the typical eukaryotic messenger RNA before it can be used to produce a correct protein through translation...
of metazoan histone
Histone
In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation...
pre-mRNAs, which are spliced by a different mechanism than nuclear
Cell nucleus
In cell biology, the nucleus is a membrane-enclosed organelle found in eukaryotic cells. It contains most of the cell's genetic material, organized as multiple long linear DNA molecules in complex with a large variety of proteins, such as histones, to form chromosomes. The genes within these...
pre-mRNAs and self-splicing intron
Intron
An intron is any nucleotide sequence within a gene that is removed by RNA splicing to generate the final mature RNA product of a gene. The term intron refers to both the DNA sequence within a gene, and the corresponding sequence in RNA transcripts. Sequences that are joined together in the final...
s. The 5' end of U7 RNA is thought to base-pair to a conserved spacer element downstream of the cleavage site in histone pre-mRNA.