Trisamine (abbreviated TPA) is an organic compound

Organic compound

An organic compound is any member of a large class of gaseous, liquid, or solid chemical compounds whose molecules contain carbon. For historical reasons discussed below, a few types of carbon-containing compounds such as carbides, carbonates, simple oxides of carbon, and cyanides, as well as the...

 with the formula (C₅H₄NCH₂)₃N. This colorless solid is used as a ligand in coordination chemistry.

The ligand is prepared by the alkylation of picolylamine by picolyl chloride:

2 C₅H₄NCH₂Cl + C₅H₄NCH₂NH₂ → (C₅H₄NCH₂)₃N + 2 HCl

TPA is a tripodal ligand, often used to simulate the coordination environment provided by some proteins.