Translocase
Encyclopedia
Translocase is a general term for an enzyme that assists in moving another molecule, usually across a membrane.
Translocases are most common secretion system in Gram positive bacteria
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Examples include:
Translocases are most common secretion system in Gram positive bacteria
Bacteria
Bacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...
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Examples include:
- ornithine translocaseOrnithine translocaseOrnithine translocase is responsible for transporting ornithine from the cytosol into the mitochondria in the urea cycle.-Pathology:A disorder is associated with ornithine translocase deficiency, and a form of hyperammonemia....
(SLC25A15), associated with ornithine translocase deficiencyOrnithine translocase deficiencyOrnithine translocase deficiency, also called Hyperornithinemia-Hyperammonemia-Homocitrullinuria syndrome, is a rare autosomal recessive urea cycle disorder affecting the enzyme ornithine translocase, which causes ammonia to accumulate in the blood, a condition called hyperammonemia.Ammonia, which...
. - carnitine-acylcarnitine translocaseCarnitine-acylcarnitine translocaseCarnitine-acylcarnitine translocases are responsible for transporting both carnitine and carnitine-fatty acid complexes into and out of the mitochondria, across the inner mitochondrial membrane.-Function:...
(SLC25A20), associated with carnitine-acylcarnitine translocase deficiencyCarnitine-acylcarnitine translocase deficiencyCarnitine-acylcarnitine translocase deficiency is a rare, autosomal recessive metabolic disorder that prevents the body from converting long-chain fatty acids into energy, particularly during periods without food. Carnitine, a natural substance acquired mostly through the diet, is used by cells to...
. - Translocase of outer mitochondrial membrane 40 (TOMM40TOMM40Translocase of outer mitochondrial membrane 40 homolog , also known as TOMM40, is a protein which in humans is encoded by the TOMM40 gene.-Function:...
), a protein encoded by the TOMM40 gene, whose alleles differentially impact the risk for Alzheimer's diseaseAlzheimer's diseaseAlzheimer's disease also known in medical literature as Alzheimer disease is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death...